Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover
about
A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat.RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathwaysThe prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancerThe human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediatorSignaling and epigenetic regulation of pituitary developmentIdentification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1A Foxo/Notch pathway controls myogenic differentiation and fiber type specificationWidespread mRNA polyadenylation events in introns indicate dynamic interplay between polyadenylation and splicingNotch Signaling in Neuroendocrine TumorsMediator kinase module and human tumorigenesisMediator-dependent nuclear receptor functionNotch signaling in prostate cancer: a moving targetFrom fly wings to targeted cancer therapies: a centennial for notch signalingLoss of PTB or negative regulation of Notch mRNA reveals distinct zones of Notch and actin protein accumulation in Drosophila embryoCharacterization of two distinct lymphoproliferative diseases caused by ectopic expression of the Notch ligand DLL4 on T cellsStructure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogasterRAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription ComplexConformational Locking upon Cooperative Assembly of Notch Transcription ComplexesCharacterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodiesNOTCH receptors in gastric and other gastrointestinal cancers: oncogenes or tumor suppressors?Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.MicroRNA-101 is a potential prognostic indicator of laryngeal squamous cell carcinoma and modulates CDK8Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1The Mediator Kinase Module Restrains Epidermal Growth Factor Receptor Signaling and Represses Vulval Cell Fate Specification in Caenorhabditis elegansThe human Mediator complex: a versatile, genome-wide regulator of transcriptionCDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon responseCDK8 is a colorectal cancer oncogene that regulates beta-catenin activityThe Mediator complex and transcription regulationGlycogen synthase kinase 3 beta positively regulates Notch signaling in vascular smooth muscle cells: role in cell proliferation and survivalPten coordinates retinal neurogenesis by regulating Notch signallingThe tyrosine kinase c-Src directly mediates growth factor-induced Notch-1 and Furin interaction and Notch-1 activation in pancreatic cancer cellsAssessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinasesThe canonical Notch signaling pathway: unfolding the activation mechanism.Notch signalling: a simple pathway becomes complexControl of the embryonic stem cell stateTumor-suppressive effects of CDK8 in endometrial cancer cells.NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair.Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition
P2860
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P2860
Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@ast
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@en
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@en-gb
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@nl
type
label
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@ast
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@en
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@en-gb
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@nl
prefLabel
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@ast
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@en
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@en-gb
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@nl
P2093
P921
P3181
P1433
P1476
Mastermind recruits CycC:CDK8 ...... inate activation with turnover
@en
P2093
Christy J Fryer
J Brandon White
Katherine A Jones
P304
P3181
P356
10.1016/J.MOLCEL.2004.10.014
P407
P577
2004-11-19T00:00:00Z