Recombinant PML adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis
about
Sequestration and inhibition of Daxx-mediated transcriptional repression by PMLThe growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylasesPML colocalizes with and stabilizes the DNA damage response protein TopBP1PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2The promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoterGene therapy for carcinoma of the breast: Pro-apoptotic gene therapyPromyelocytic leukemia protein PML inhibits Nur77-mediated transcription through specific functional interactionsPML interaction with p53 and its role in apoptosis and replicative senescenceThe promyelocytic leukemia protein represses A20-mediated transcriptionGenes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signalingPondering the puzzle of PML (promyelocytic leukemia) nuclear bodies: can we fit the pieces together using an RNA regulon?Transfection of promyelocytic leukemia in retrovirus vector inhibits growth of human bladder cancer cells.Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemiaPondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodies.ATP directed agent, 8-chloro-adenosine, induces AMP activated protein kinase activity, leading to autophagic cell death in breast cancer cells.Transforming potential of the adenovirus type 5 E4orf3 protein.Acute promyelocytic leukemia: from treatment to genetics and back.Retinoids in chemoprevention and differentiation therapy.The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cellsDeconstructing PML-induced premature senescence.Suppressed expression of T-box transcription factors is involved in senescence in chronic obstructive pulmonary disease.Promyelocytic leukemia inhibits adipogenesis, and loss of promyelocytic leukemia results in fat accumulation in mice.Acute promyelocytic leukemia: PML/RARalpha and the leukemic stem cell.Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 cells.New insights into the role of PML in tumour suppression.The human promyelocytic leukemia protein is a tumor suppressor for murine skin carcinogenesisRegulation of apoptosis by PML and the PML-NBs.The role of PML in the nervous system.TRIMming p53's anticancer activity.Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression.Promyelocytic leukemia protein sensitizes tumor necrosis factor alpha-induced apoptosis by inhibiting the NF-kappaB survival pathway.LATS1 tumor suppressor regulates G2/M transition and apoptosis.Heregulin-induced apoptosis is mediated by down-regulation of Bcl-2 and activation of caspase-7 and is potentiated by impairment of protein kinase C alpha activity.Interferon-beta induces S phase slowing via up-regulated expression of PML in squamous carcinoma cells.The promyelocytic leukemia (PML) protein suppresses cyclin D1 protein production by altering the nuclear cytoplasmic distribution of cyclin D1 mRNA.Regulation of AML2/CBFA3 in hematopoietic cells through the retinoic acid receptor alpha-dependent signaling pathway.Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies.PML: An emerging tumor suppressor and a target with therapeutic potential.The retinoblastoma protein and PML collaborate to organize heterochromatin and silence E2F-responsive genes during senescence.Promyelocytic leukemia protein-induced growth suppression and cell death in liver cancer cells.
P2860
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P2860
Recombinant PML adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@ast
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@en
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@en-gb
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@nl
type
label
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@ast
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@en
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@en-gb
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@nl
prefLabel
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@ast
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@en
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@en-gb
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@nl
P2093
P356
P1433
P1476
Recombinant PML adenovirus sup ...... ell cycle arrest and apoptosis
@en
P2093
P2888
P304
P356
10.1038/SJ.ONC.1201705
P407
P577
1998-04-09T00:00:00Z
P5875
P6179
1026515303