Structural and biochemical studies of TIGAR (TP53-induced glycolysis and apoptosis regulator)
about
Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell deathModulation of intracellular ROS levels by TIGAR controls autophagyInsulin-like Growth Factor 1 Signaling Axis Meets p53 Genome Protection PathwaysStructure and Activity of the Metal-independent Fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiaeChemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased CarcinogenesisActivation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver diseaseTIGAR is required for efficient intestinal regeneration and tumorigenesisp53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress.Tumor suppressor p53 and estrogen receptors in nuclear-mitochondrial communication.Regulation of pyruvate metabolism and human diseaseTIGAR induces p53-mediated cell-cycle arrest by regulation of RB-E2F1 complexHexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy.Stromal-epithelial metabolic coupling in cancer: integrating autophagy and metabolism in the tumor microenvironment.TIGAR is correlated with maximal standardized uptake value on FDG-PET and survival in non-small cell lung cancer.Targeting the p53 signaling pathway in cancer therapy - the promises, challenges and perils.Alterations of metabolic genes and metabolites in cancer.Functional changes in mRNA expression and alternative pre-mRNA splicing associated with the effects of nutrition on apoptosis and spermatogenesis in the adult testis.Nutrient-sensing mTORC1: Integration of metabolic and autophagic signalsMetabolic regulation by p53 family members.NF-κB protein expression associates with (18)F-FDG PET tumor uptake in non-small cell lung cancer: a radiogenomics validation study to understand tumor metabolism.Cancer cell metabolism and the modulating effects of nitric oxide.Ursolic Acid-Regulated Energy Metabolism-Reliever or Propeller of Ultraviolet-Induced Oxidative Stress and DNA Damage?p53 regulation of metabolic pathways.Enzymatic features of the glucose metabolism in tumor cells.Metabolism and brain cancer.Targeting lactate metabolism for cancer therapeutics.Glucose and glutamine metabolism control by APC and SCF during the G1-to-S phase transition of the cell cycle.Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells.Melatonin ameliorates hypoglycemic stress-induced brain endothelial tight junction injury by inhibiting protein nitration of TP53-induced glycolysis and apoptosis regulator (TIGAR).Endothelial ErbB4 deficit induces alterations in exploratory behavior and brain energy metabolism in mice.Regulation of Cellular Metabolism and Hypoxia by p53.Cellular lifespan and senescence: a complex balance between multiple cellular pathways.Metabolic alterations during the growth of tumour spheroids.Regulation of Metabolic Activity by p53.TIGAR, TIGAR, burning bright.TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency.The Pentose Phosphate Pathway as a Potential Target for Cancer Therapy.The human T-cell leukemia virus type-1 p30II protein activates p53 and induces the TIGAR and suppresses oncogene-induced oxidative stress during viral carcinogenesis.DNA Damage, Repair, and Cancer Metabolism.The fructose-2,6-bisphosphatase TIGAR suppresses NF-κB signaling by directly inhibiting the linear ubiquitin assembly complex LUBAC.
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P2860
Structural and biochemical studies of TIGAR (TP53-induced glycolysis and apoptosis regulator)
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural and biochemical stu ...... lysis and apoptosis regulator)
@ast
Structural and biochemical stu ...... lysis and apoptosis regulator)
@en
Structural and biochemical stu ...... lysis and apoptosis regulator)
@en-gb
Structural and biochemical stu ...... lysis and apoptosis regulator)
@nl
type
label
Structural and biochemical stu ...... lysis and apoptosis regulator)
@ast
Structural and biochemical stu ...... lysis and apoptosis regulator)
@en
Structural and biochemical stu ...... lysis and apoptosis regulator)
@en-gb
Structural and biochemical stu ...... lysis and apoptosis regulator)
@nl
prefLabel
Structural and biochemical stu ...... lysis and apoptosis regulator)
@ast
Structural and biochemical stu ...... lysis and apoptosis regulator)
@en
Structural and biochemical stu ...... lysis and apoptosis regulator)
@en-gb
Structural and biochemical stu ...... lysis and apoptosis regulator)
@nl
P2860
P921
P3181
P356
P1476
Structural and biochemical stu ...... lysis and apoptosis regulator)
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M807821200
P407
P577
2009-01-16T00:00:00Z