Alterations of metabolic genes and metabolites in cancer.
about
Lactate dehydrogenase A in cancer: a promising target for diagnosis and therapyIsocitrate dehydrogenase mutations: new opportunities for translational researchNutrient sensing, metabolism, and cell growth controlRole of TET enzymes in DNA methylation, development, and cancerPreoperative blood-routine markers and prognosis of esophageal squamous cell carcinoma: The Fujian prospective investigation of cancer (FIESTA) study.Rapamycin (mTORC1 inhibitor) reduces the production of lactate and 2-hydroxyglutarate oncometabolites in IDH1 mutant fibrosarcoma cellsInhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressorsCancer genomic research at the crossroads: realizing the changing genetic landscape as intratumoral spatial and temporal heterogeneity becomes a confounding factor.Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic activity.Repression of Hox genes by LMP1 in nasopharyngeal carcinoma and modulation of glycolytic pathway genes by HoxC8.IDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human glioma.Targeting cancer metabolism.Acetoacetate Accelerates Muscle Regeneration and Ameliorates Muscular Dystrophy in Mice.What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer.CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function.Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes.Induction of sarcomas by mutant IDH2Anti-inflammatory and Antitumor Activity of a Triple Therapy for a Colitis-Related Colorectal Cancer.A review of applications of metabolomics in cancer.Metabolic mechanisms of epigenetic regulation.IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectivesMetabolic alteration in tumorigenesis.Effects of deranged metabolism on epigenetic changes in cancer.Metabolic rewiring of pancreatic ductal adenocarcinoma: New routes to follow within the maze.The application of genome-wide 5-hydroxymethylcytosine studies in cancer research.Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.D-2-Hydroxyglutarate does not mimic all the IDH mutation effects, in particular the reduced etoposide-triggered apoptosis mediated by an alteration in mitochondrial NADH.TRPC Channels and Glioma.R-2-hydroxyglutarate as the key effector of IDH mutations promoting oncogenesis.Isocitrate dehydrogenases in physiology and cancer: biochemical and molecular insight.The mechanisms of IDH mutations in tumorigenesis.Clinical Applications of Contrast-Enhanced Perfusion MRI Techniques in Gliomas: Recent Advances and Current Challenges.Succinate dehydrogenase deficiency is associated with decreased 5-hydroxymethylcytosine production in gastrointestinal stromal tumors: implications for mechanisms of tumorigenesis.Genetic variations in IDH gene as prognosis predictors in TACE-treated hepatocellular carcinoma patients.Familial hematological malignancies: new IDH2 mutation.Metabolic Alterations in Cancer Cells and the Emerging Role of Oncometabolites as Drivers of Neoplastic Change.Tissue metabolite profiling identifies differentiating and prognostic biomarkers for prostate carcinoma.
P2860
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P2860
Alterations of metabolic genes and metabolites in cancer.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Alterations of metabolic genes and metabolites in cancer.
@ast
Alterations of metabolic genes and metabolites in cancer.
@en
type
label
Alterations of metabolic genes and metabolites in cancer.
@ast
Alterations of metabolic genes and metabolites in cancer.
@en
prefLabel
Alterations of metabolic genes and metabolites in cancer.
@ast
Alterations of metabolic genes and metabolites in cancer.
@en
P2093
P2860
P1476
Alterations of metabolic genes and metabolites in cancer.
@en
P2093
Eric K Oermann
Kun-Liang Guan
P2860
P304
P356
10.1016/J.SEMCDB.2012.01.013
P577
2012-01-28T00:00:00Z