The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels
about
AIP4/Itch regulates Notch receptor degradation in the absence of ligandPCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradationArresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4.The puzzle of TRPV4 channelopathies.Late domain-independent rescue of a release-deficient Moloney murine leukemia virus by the ubiquitin ligase itch.Nedd4-1 and beta-arrestin-1 are key regulators of Na+/H+ exchanger 1 ubiquitylation, endocytosis, and functionShear stress mediates exocytosis of functional TRPV4 channels in endothelial cells.STAM and Hrs down-regulate ciliary TRP receptorsPlasticity of polyubiquitin recognition as lysosomal targeting signals by the endosomal sorting machinery.The roles of G proteins in the activation of TRPC4 and TRPC5 transient receptor potential channels.Human skeletal dysplasia caused by a constitutive activated transient receptor potential vanilloid 4 (TRPV4) cation channel mutation.Protein monoubiquitylation: targets and diverse functionsTRPP2 and TRPV4 form a polymodal sensory channel complex.Pooled RNAi screen identifies ubiquitin ligase Itch as crucial for influenza A virus release from the endosome during virus entry.Transient receptor potential channels in bladder function.Trafficking of ThermoTRP Channels.TRPV4: physiological role and therapeutic potential in respiratory diseases.The E3 ligase Itch in immune regulation and beyond.Tyrosine phosphorylation modulates the activity of TRPV4 in response to defined stimuli.The E3 ligase Itch knockout mice show hyperproliferation and wound healing alteration.TRPV4 plays a role in breast cancer cell migration via Ca2+-dependent activation of AKT and downregulation of E-cadherin cell cortex protein.Extracellular LDLR repeats modulate Wnt signaling activity by promoting LRP6 receptor endocytosis mediated by the Itch E3 ubiquitin ligase.Epithelial sodium channel (ENaC) is multi-ubiquitinated at the cell surface.Impaired capsaicin-induced relaxation of coronary arteries in a porcine model of the metabolic syndrome.
P2860
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P2860
The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@ast
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@en
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@en-gb
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@nl
type
label
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@ast
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@en
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@en-gb
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@nl
prefLabel
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@ast
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@en
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@en-gb
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@nl
P2093
P2860
P356
P1433
P1476
The HECT ubiquitin ligase AIP4 ...... ression of select TRP channels
@en
P2093
Kerstin Hill
Michael Schaefer
P2860
P304
P356
10.1038/SJ.EMBOJ.7601429
P407
P577
2006-11-16T00:00:00Z