Allele-specific silencing of a pathogenic mutant acetylcholine receptor subunit by RNA interference
about
A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sitesDecoding the riddle: the dawn of RNAi for the study of gene-gene and gene-environment interactionsDesigning siRNA that distinguish between genes that differ by a single nucleotideDesign of RNAi hairpins for mutation-specific silencing of ataxin-7 and correction of a SCA7 phenotype.Decoding pathogenesis of slow-channel congenital myasthenic syndromes using recombinant expression and mice models.Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cellsAllele-specific silencing of mutant Huntington's disease gene.Therapeutic potential of antisense nucleic acid molecules.Unravelling the general properties of siRNAs: strength in numbers and lessons from the past.Silencing neurodegenerative disease: bringing RNA interference to the clinic.Modulating the expression of disease genes with RNA-based therapy.Allele-specific silencing of the dominant disease allele in sialuria by RNA interference.Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant alleles.Short non-coding RNA biology and neurodegenerative disorders: novel disease targets and therapeutics.Further observations in congenital myasthenic syndromesDisease-causing allele-specific silencing by RNA interference.Design of efficient DNAzymes against muscle AChR alpha-subunit cRNA in vitro and in HEK 293 cells.RNAi: a potential new class of therapeutic for human genetic disease.RNA therapy for polyglutamine neurodegenerative diseases.Non-coding RNAs in crop genetic modification: considerations and predictable environmental risk assessments (ERA).Allele-specific cancer cell killing in vitro and in vivo targeting a single-nucleotide polymorphism in POLR2A.Asymmetrically designed siRNAs and shRNAs enhance the strand specificity and efficacy in RNAi.Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference.Essential notes regarding the design of functional siRNAs for efficient mammalian RNAi.Selective cleavage of AChR cRNAs harbouring mutations underlying the slow channel myasthenic syndrome by hammerhead ribozymes.Allele-specific RNA interference in FOP silencing the FOP gene.In vitro and in vivo suppression of GJB2 expression by RNA interference.
P2860
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P2860
Allele-specific silencing of a pathogenic mutant acetylcholine receptor subunit by RNA interference
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Allele-specific silencing of a ...... or subunit by RNA interference
@ast
Allele-specific silencing of a ...... or subunit by RNA interference
@en
Allele-specific silencing of a ...... or subunit by RNA interference
@en-gb
Allele-specific silencing of a ...... or subunit by RNA interference
@nl
type
label
Allele-specific silencing of a ...... or subunit by RNA interference
@ast
Allele-specific silencing of a ...... or subunit by RNA interference
@en
Allele-specific silencing of a ...... or subunit by RNA interference
@en-gb
Allele-specific silencing of a ...... or subunit by RNA interference
@nl
prefLabel
Allele-specific silencing of a ...... or subunit by RNA interference
@ast
Allele-specific silencing of a ...... or subunit by RNA interference
@en
Allele-specific silencing of a ...... or subunit by RNA interference
@en-gb
Allele-specific silencing of a ...... or subunit by RNA interference
@nl
P356
P1476
Allele-specific silencing of a ...... or subunit by RNA interference
@en
P2093
Amr Abdelgany
David Beeson
P304
P356
10.1093/HMG/DDG280
P407
P577
2003-08-19T00:00:00Z