Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2 - Wikidata - wikimedia - TriplyDB

Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2

Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2

http://www.wikidata.org/entity/Q24317630

about

Cyclic AMP-dependent transcriptional up-regulation of phosphodiesterase 4D5 in human airway smooth muscle cells. Identification and characterization of a novel PDE4D5 promoter Molecular cloning and subcellular distribution of the novel PDE4B4 cAMP-specific phosphodiesterase isoform Genomic organization of the human phosphodiesterase PDE11A gene. Evolutionary relatedness with other PDEs containing GAF domains Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition TAPAS-1, a novel microdomain within the unique N-terminal region of the PDE4A1 cAMP-specific phosphodiesterase that allows rapid, Ca2+-triggered membrane association with selectivity for interaction with phosphatidic acid Human PDE4A8, a novel brain-expressed PDE4 cAMP-specific phosphodiesterase that has undergone rapid evolutionary change Differential expression and regulation of the cAMP-selective phosphodiesterase type 4A splice variants in rat brain by chronic antidepressant administration Mice deficient in phosphodiesterase-4A display anxiogenic-like behavior S-adenosylmethionine decreases lipopolysaccharide-induced phosphodiesterase 4B2 and attenuates tumor necrosis factor expression via cAMP/protein kinase A pathway.PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression.Expression, intracellular distribution and basis for lack of catalytic activity of the PDE4A7 isoform encoded by the human PDE4A cAMP-specific phosphodiesterase gene Sub-family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP-specific phosphodiesterases.Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells.The Past, Present, and Future of Phosphodiesterase-4 Modulation for Age-Induced Memory Loss.

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P2860

Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2

http://www.wikidata.org/entity/Q24317630

description

1998 nî lūn-bûn

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1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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1998 թվականի օգոստոսին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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Identification and characteriz ...... located at chromosome 19p13.2

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Identification and characteriz ...... located at chromosome 19p13.2

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Identification and characteriz ...... located at chromosome 19p13.2

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Identification and characteriz ...... located at chromosome 19p13.2

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Identification and characteriz ...... located at chromosome 19p13.2

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Identification and characteriz ...... located at chromosome 19p13.2

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Identification and characteriz ...... located at chromosome 19p13.2

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Identification and characteriz ...... located at chromosome 19p13.2

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Identification and characteriz ...... located at chromosome 19p13.2

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Identification and characteriz ...... located at chromosome 19p13.2

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Identification and characteriz ...... located at chromosome 19p13.2

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Identification and characteriz ...... located at chromosome 19p13.2

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Biochemical Journal

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Identification and characteriz ...... located at chromosome 19p13.2.

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A S Olsen

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F Begg

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L Gordon

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M Sullivan

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P2860

Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene

Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases

A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs

Molecular cloning and characterization of mammalian homologues of the Drosophila retinal degeneration B gene

Molecular cloning of a novel splice variant of human type IVA (PDE-IVA) cyclic AMP phosphodiesterase and localization of the gene to the p13.2-q12 region of human chromosome 19 [corrected]

Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3

Cloning and expression of cDNA for a human low-Km, rolipram-sensitive cyclic AMP phosphodiesterase

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Determination of the structure of the N-terminal splice region of the cyclic AMP-specific phosphodiesterase RD1 (RNPDE4A1) by 1H NMR and identification of the membrane association domain using chimeric constructs

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693-703

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scholarly article

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10.1042/BJ3330693

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P407

P478

333 ( Pt 3)

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Miles D. Houslay

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1998-08-01T00:00:00Z

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13608389

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9677330

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Phosphodiesterase 4A

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1219634

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