Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase
about
Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85alpha Src homology 2 domains with phosphoinositides and inositol polyphosphatesAlternative modes of binding of proteins with tandem SH2 domainsSolution structure and backbone dynamics of the non-receptor protein-tyrosine kinase-6 Src homology 2 domainDynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its ActivityUsing a phage display library to identify basic residues in A-Raf required to mediate binding to the Src homology 2 domains of the p85 subunit of phosphatidylinositol 3'-kinase.Combinatorial Domain Hunting: An effective approach for the identification of soluble protein domains adaptable to high-throughput applications.Somatic mutations in PI3Kalpha: structural basis for enzyme activation and drug designExperimental mapping of soluble protein domains using a hierarchical approachThe smaller isoforms of ankyrin 3 bind to the p85 subunit of phosphatidylinositol 3'-kinase and enhance platelet-derived growth factor receptor down-regulation.Epstein-Barr virus latent membrane protein 2A preferentially signals through the Src family kinase LynRegulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110alpha and are disrupted in oncogenic p85 mutantsThe regulation of class IA PI 3-kinases by inter-subunit interactions.Structural insights into the intertwined dimer of fyn SH2Specific binding of the C-terminal Src homology 2 domain of the p85alpha subunit of phosphoinositide 3-kinase to phosphatidylinositol 3,4,5-trisphosphate. Localization and engineering of the phosphoinositide-binding motif.Computational models of tandem SRC homology 2 domain interactions and application to phosphoinositide 3-kinase.New Insights into PI3K Inhibitor Design using X-ray Structures of PI3Kα Complexed with a Potent Lead Compound.A putative role of the Sup35p C-terminal domain in the cytoskeleton organization during yeast mitosis.Dynamic Allostery in PLCγ1 and Its Modulation by a Cancer Mutation Revealed by MD Simulation and NMR
P2860
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P2860
Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@ast
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@en
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@en-gb
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@nl
type
label
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@ast
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@en
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@en-gb
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@nl
prefLabel
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@ast
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@en
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@en-gb
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@nl
P2093
P356
P1476
Solution structure of the C-te ...... t of phosphoinositide 3-kinase
@en
P2093
G Panayotou
M D Waterfield
P C Driscoll
S M Kristensen
P304
P356
10.1006/JMBI.1997.1562
P407
P577
1998-02-20T00:00:00Z