Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
about
Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger proteinTranscription factor gene AP-2 gamma essential for early murine developmentDefective human interleukin 2 receptor gamma chain in an atypical X chromosome-linked severe combined immunodeficiency with peripheral T cellsUtilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15Therapeutic targeting of Janus kinasesDNA array analysis of interleukin-2-regulated immediate/early genesThe quantal theory of how the immune system discriminates between "self and non-self"In vivo mucosal delivery of bioactive human interleukin 1 receptor antagonist produced by Streptococcus gordoniiInducible model for beta-six-mediated site-specific recombination in mammalian cells.FOXP3(+) Treg Cells and Gender Bias in Autoimmune DiseasesRegulation generation: the suppressive functions of human regulatory T cellsFrom IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokinesDaclizumab therapy for multiple sclerosisStimulation of interferon regulatory factor-1 by prolactinInterleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiationGeneration of nitric oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon gamma receptorMurine Schnurri-2 is required for positive selection of thymocytesImpairment of T cell development in deltaEF1 mutant miceLarge functional repertoire of regulatory T-cell suppressible autoimmune T cells in scurfy mice.Response to influenza infection in mice with a targeted disruption in the interferon gamma geneComplementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesisNegative feedback regulation of T cells via interleukin-2 and FOXP3 reciprocity.Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice.Specificity of signaling by hematopoietic cytokine receptors: instructive versus permissive effects.Walking through the forest of transgenic models of human disease.Cytokines in asthma.The common gamma chain cytokines interleukin (IL)-2 and IL-7 indirectly modulate blood fluke development via effects on CD4+ T cells.When immunization leads to autoimmunity: chronic inflammation as a result of thymic and mucosal dysregulation in IL-2 knock-out mice.Cell-to-cell interactions and signals involved in the reconstitution of peripheral CD8 T(CM) and T(EM) cell pools.Pathways of T cell pathology in models of chronic intestinal inflammation.Interleukin-2 receptor downstream events in regulatory T cells: implications for the choice of immunosuppressive drug therapyInterleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro.Extra-thymically induced regulatory T cells: do they have potential in disease prevention?The IL-2 defect in systemic lupus erythematosus disease has an expansive effect on host immunityNovel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locusCellular therapies supplement: the role of granulocyte macrophage colony-stimulating factor and dendritic cells in regulatory T-cell homeostasis and expansion.Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell deathNaive T cells proliferate strongly in neonatal mice in response to self-peptide/self-MHC complexes.Presentation at the National Asthma Campaign International Congress, June 1999. Controlling the inflammatory response through transcriptional mechanisms.
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P2860
Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
description
1991 nî lūn-bûn
@nan
1991 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Development and function of T ...... -2 deficient by gene targeting
@ast
Development and function of T ...... -2 deficient by gene targeting
@en
Development and function of T ...... -2 deficient by gene targeting
@en-gb
Development and function of T ...... -2 deficient by gene targeting
@nl
type
label
Development and function of T ...... -2 deficient by gene targeting
@ast
Development and function of T ...... -2 deficient by gene targeting
@en
Development and function of T ...... -2 deficient by gene targeting
@en-gb
Development and function of T ...... -2 deficient by gene targeting
@nl
prefLabel
Development and function of T ...... -2 deficient by gene targeting
@ast
Development and function of T ...... -2 deficient by gene targeting
@en
Development and function of T ...... -2 deficient by gene targeting
@en-gb
Development and function of T ...... -2 deficient by gene targeting
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P356
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Development and function of T ...... -2 deficient by gene targeting
@en
P2093
P2888
P356
10.1038/352621A0
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P577
1991-08-15T00:00:00Z
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P6179
1015644987