Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein
about
The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3Cooperative interaction between ETS1 and GFI1 transcription factors in the repression of Bax gene expressionGfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1A role of Miz-1 in Gfi-1-mediated transcriptional repression of CDKN1AThe Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation.Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factorEpigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5Zinc finger protein Gfi1 controls the endotoxin-mediated Toll-like receptor inflammatory response by antagonizing NF-kappaB p65The transcriptional repressor GFI-1 antagonizes PU.1 activity through protein-protein interactionGATA-1 mediates auto-regulation of Gfi-1B transcription in K562 cellsTargeted transcriptional repression of Gfi1 by GFI1 and GFI1B in lymphoid cellsGATA-1 and NF-Y cooperate to mediate erythroid-specific transcription of Gfi-1B geneMutations in proto-oncogene GFI1 cause human neutropenia and target ELA2Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressorDirect transcriptional repression of the genes encoding the zinc-finger proteins Gfi1b and Gfi1 by Gfi1bFrom cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formationFactors and networks that underpin early hematopoiesisIdentification of a novel human kinase supporter of Ras (hKSR-2) that functions as a negative regulator of Cot (Tpl2) signalingReplacement of interleukin-2 (IL-2)-generated mitogenic signals by a mink cell focus-forming (MCF) or xenotropic virus-induced IL-9-dependent autocrine loop: implications for MCF virus-induced leukemogenesisDifferentiation of effector CD4 T cell populations (*)Correlation of two-hybrid affinity data with in vitro measurementsGrowth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia.Transcriptional repressor Gfi1 integrates cytokine-receptor signals controlling B-cell differentiation.Loss of the transcriptional repressor PAG-3/Gfi-1 results in enhanced neurosecretion that is dependent on the dense-core vesicle membrane protein IDA-1/IA-2.The transcription factor Gfi1 regulates G-CSF signaling and neutrophil development through the Ras activator RasGRP1.Gfi1-Cre knock-in mouse line: A tool for inner ear hair cell-specific gene deletion.Novel therapeutic targets in myeloma bone disease.A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia.Repression of Id2 expression by Gfi-1 is required for B-cell and myeloid developmentEnhancer hijacking activates GFI1 family oncogenes in medulloblastoma.E2A-HLF usurps control of evolutionarily conserved survival pathways.Growth factor-independent 1B gene (GFI1B) is overexpressed in erythropoietic and megakaryocytic malignancies and increases their proliferation rate.The enhancer of trithorax and polycomb gene Caf1/p55 is essential for cell survival and patterning in Drosophila developmentGFI1 is repressed by p53 and inhibits DNA damage-induced apoptosis.Growth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.Targets of the transcriptional repressor oncoprotein Gfi-1.Genetic profile of insertion mutations in mouse leukemias and lymphomas.Regulation of cytokine receptor signaling by SOCS1.Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion.The downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 axis and by human cytomegalovirus (HCMV) associated factors allows the activation of the HCMV major IE promoter and the transition to productive infection.
P2860
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P2860
Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@ast
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@en
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@en-gb
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@nl
type
label
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@ast
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@en
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@en-gb
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@nl
prefLabel
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@ast
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@en
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@en-gb
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@nl
P2093
P2860
P921
P3181
P356
P1476
Progression of interleukin-2 ( ...... ng a novel zinc finger protein
@en
P2093
H L Grimes
P N Tsichlis
P2860
P304
P3181
P356
10.1128/MCB.13.3.1759
P407
P577
1993-03-01T00:00:00Z