Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly
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Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteinsStructure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenitaSolution structure of the core SMN–Gemin2 complexStructural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5The SMN structure reveals its crucial role in snRNP assemblyProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical spaceArchaeal and eukaryotic homologs of Hfq: A structural and evolutionary perspective on Sm function.Spinal Muscular Atrophy: From Defective Chaperoning of snRNP Assembly to Neuromuscular Dysfunction.Invertebrate models of spinal muscular atrophy: insights into mechanisms and potential therapeutics.GEMINs: potential therapeutic targets for spinal muscular atrophy?Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control.Multi-disciplinary methods to define RNA-protein interactions and regulatory networksThe Gemin associates of survival motor neuron are required for motor function in Drosophila.Advances in therapeutic development for spinal muscular atrophy.Genetic Interactions between the Members of the SMN-Gemins Complex in Drosophila.The spliceosome assembly factor GEMIN2 attenuates the effects of temperature on alternative splicing and circadian rhythms.Oligomeric Properties of Survival Motor Neuron·Gemin2 ComplexesReconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organizationNUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins.How do SMA-linked mutations of SMN1 lead to structural/functional deficiency of the SMA protein?A U1 snRNP-specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchangeA novel human-specific splice isoform alters the critical C-terminus of Survival Motor Neuron protein.Structure-function analysis and genetic interactions of the SmG, SmE, and SmF subunits of the yeast Sm protein ring.Dysregulation of synaptogenesis genes antecedes motor neuron pathology in spinal muscular atrophy.Fam118B, a newly identified component of Cajal bodies, is required for Cajal body formation, snRNP biogenesis and cell viability.The search for evolutionary developmental origins of aging in zebrafish: a novel intersection of developmental and senescence biology in the zebrafish model system.Spliceosomal small nuclear ribonucleoprotein biogenesis defects and motor neuron selectivity in spinal muscular atrophy.Structure and RNA-binding properties of the bacterial LSm protein Hfq.A day in the life of the spliceosomeNovel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans.Gem depletion: amyotrophic lateral sclerosis and spinal muscular atrophy crossover.SMN control of RNP assembly: from post-transcriptional gene regulation to motor neuron disease.Nervous translation, do you get the message? A review of mRNPs, mRNA-protein interactions and translational control within cells of the nervous system.Re-refinement of the spliceosomal U4 snRNP core-domain structure.UsnRNP biogenesis: mechanisms and regulation.Advances in understanding the role of disease-associated proteins in spinal muscular atrophy.SMN - A chaperone for nuclear RNP social occasions?Diverse role of survival motor neuron protein.SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation.SMA-causing missense mutations in survival motor neuron (Smn) display a wide range of phenotypes when modeled in Drosophila.
P2860
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P2860
Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structure of a key intermediat ...... ial function in snRNP assembly
@ast
Structure of a key intermediat ...... ial function in snRNP assembly
@en
Structure of a key intermediat ...... ial function in snRNP assembly
@en-gb
Structure of a key intermediat ...... ial function in snRNP assembly
@nl
type
label
Structure of a key intermediat ...... ial function in snRNP assembly
@ast
Structure of a key intermediat ...... ial function in snRNP assembly
@en
Structure of a key intermediat ...... ial function in snRNP assembly
@en-gb
Structure of a key intermediat ...... ial function in snRNP assembly
@nl
altLabel
Structure of a Key Intermediat ...... ial Function in snRNP Assembly
@en
prefLabel
Structure of a key intermediat ...... ial function in snRNP assembly
@ast
Structure of a key intermediat ...... ial function in snRNP assembly
@en
Structure of a key intermediat ...... ial function in snRNP assembly
@en-gb
Structure of a key intermediat ...... ial function in snRNP assembly
@nl
P2093
P2860
P3181
P1433
P1476
Structure of a key intermediat ...... ial function in snRNP assembly
@en
P2093
Byung Ran So
Gideon Dreyfuss
Jeongsik Yong
Rundong Zhang
Tina Glisovic
P2860
P304
P3181
P356
10.1016/J.CELL.2011.06.043
P407
P577
2011-08-05T00:00:00Z