Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2
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Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinaseABC50 promotes translation initiation in mammalian cellsA mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alphaIdentification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formationAssociation of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activationThe translational regulators GCN-1 and ABCF-3 act together to promote apoptosis in C. elegansThe novel ATP-binding cassette protein ARB1 is a shuttling factor that stimulates 40S and 60S ribosome biogenesis.Tandem affinity purification revealed the hypusine-dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex.Gcn1 and actin binding to Yih1: implications for activation of the eIF2 kinase GCN2.YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed.The highly conserved eukaryotic DRG factors are required for efficient translation in a manner redundant with the putative RNA helicase Slh1Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2{alpha} kinase GCN2 during amino acid starvation.Dimerization by translation initiation factor 2 kinase GCN2 is mediated by interactions in the C-terminal ribosome-binding region and the protein kinase domain.Evidence that Yih1 resides in a complex with ribosomes.Posttranscriptional control of gene expression in yeast.Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1.Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activityGcn1 contacts the small ribosomal protein Rps10, which is required for full activation of the protein kinase Gcn2.Ribosome-binding domain of eukaryotic initiation factor-2 kinase GCN2 facilitates translation control.Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation.Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells.What Is the Impact of mRNA 5' TL Heterogeneity on Translational Start Site Selection and the Mammalian Cellular Phenotype?Identification of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) as a novel target of bisphenol AIMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activationABC50 interacts with eukaryotic initiation factor 2 and associates with the ribosome in an ATP-dependent mannerIMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowthYeast dom34 mutants are defective in multiple developmental pathways and exhibit decreased levels of polyribosomesA genetic screen reveals Arabidopsis stomatal and/or apoplastic defenses against Pseudomonas syringae pv. tomato DC3000.Identification of ABC transporters in Sarcoptes scabiei.The ABC transporter gene family of Daphnia pulex.Enhanced interaction between pseudokinase and kinase domains in Gcn2 stimulates eIF2α phosphorylation in starved cellsThe role of the innate immune response regulatory gene ABCF1 in mammalian embryogenesis and developmentGenome-wide identification and evolution of ATP-binding cassette transporters in the ciliate Tetrahymena thermophila: A case of functional divergence in a multigene familytRNAs as regulators of biological processesEvolutionary analyses of ABC transporters of Dictyostelium discoideum.Gcn4p, a master regulator of gene expression, is controlled at multiple levels by diverse signals of starvation and stress.HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functionsDefects in tRNA processing and nuclear export induce GCN4 translation independently of phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase.Genome-wide identification and characterization of ATP-binding cassette transporters in the silkworm, Bombyx mori.
P2860
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P248
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P2860
Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@ast
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@en
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@en-gb
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@nl
type
label
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@ast
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@en
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@en-gb
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@nl
prefLabel
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@ast
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@en
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@en-gb
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@nl
P2093
P2860
P3181
P356
P1476
Evidence that GCN1 and GCN20, ...... ation of eIF2alpha kinase GCN2
@en
P2093
A G Hinnebusch
C R Vazquez de Aldana
K Chakraburtty
M J Marton
P2860
P304
P3181
P356
10.1128/MCB.17.8.4474
P407
P577
1997-08-01T00:00:00Z