Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
about
Orthopoxvirus genes that mediate disease virulence and host tropismFunctional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic proteinVaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligandsVaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7Structure of M11L: A myxoma virus structural homolog of the apoptosis inhibitor, Bcl-2Vaccinia Virus Proteins A52 and B14 Share a Bcl-2–Like Fold but Have Evolved to Inhibit NF-κB rather than ApoptosisInhibition of Apoptosis and NF-κB Activation by Vaccinia Protein N1 Occur via Distinct Binding Surfaces and Make Different Contributions to VirulenceStructural Insight into BH3 Domain Binding of Vaccinia Virus Antiapoptotic F1LStructural basis of Deerpox virus-mediated inhibition of apoptosisA survey of host range genes in poxvirus genomesPoxviruses and the evolution of host range and virulenceVaccinia virus protein A49 is an unexpected member of the B-cell Lymphoma (Bcl)-2 protein familyThe N Terminus of the Vaccinia Virus Protein F1L Is an Intrinsically Unstructured Region That Is Not Involved in Apoptosis Regulation.Robust intrapulmonary CD8 T cell responses and protection with an attenuated N1L deleted vaccinia virus.Caspase-dependent inhibition of mousepox replication by gzmB.Vaccinia virus protein F1L is a caspase-9 inhibitorVaccinia virus lacking the Bcl-2-like protein N1 induces a stronger natural killer cell response to infectionMultiple functions of BCL-2 family proteins.Genetic screen of a library of chimeric poxviruses identifies an ankyrin repeat protein involved in resistance to the avian type I interferon response.Genetic screen of a mutant poxvirus library identifies an ankyrin repeat protein involved in blocking induction of avian type I interferon.N1L is an ectromelia virus virulence factor and essential for in vivo spread upon respiratory infection.Structural determinants of caspase-9 inhibition by the vaccinia virus protein, F1LVariola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim.Enhancement of CD8(+) T-cell memory by removal of a vaccinia virus nuclear factor-κB inhibitor.Vaccinia Virus Protein C6 Inhibits Type I IFN Signalling in the Nucleus and Binds to the Transactivation Domain of STAT2Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain ProteinsCross-priming of cytotoxic T cells dictates antigen requisites for modified vaccinia virus Ankara vector vaccines.Sheeppox virus SPPV14 encodes a Bcl-2-like cell death inhibitor that counters a distinct set of mammalian proapoptotic proteins.Cytomegalovirus proteins vMIA and m38.5 link mitochondrial morphogenesis to Bcl-2 family proteinsVaccinia virus F1L protein promotes virulence by inhibiting inflammasome activationMitochondrial death pathways in yeast and mammalian cells.Vaccinia virus protein K7 is a virulence factor that alters the acute immune response to infectionVaccinia virus protein N2 is a nuclear IRF3 inhibitor that promotes virulencePoxvirus host range protein CP77 contains an F-box-like domain that is necessary to suppress NF-kappaB activation by tumor necrosis factor alpha but is independent of its host range function.The fowlpox virus BCL-2 homologue, FPV039, interacts with activated Bax and a discrete subset of BH3-only proteins to inhibit apoptosis.Increased ATP generation in the host cell is required for efficient vaccinia virus production.Structural biology of the Bcl-2 family and its mimicry by viral proteinsPoxvirus proteomics and virus-host protein interactions.Deletion of the vaccinia virus N2L gene encoding an inhibitor of IRF3 improves the immunogenicity of modified vaccinia virus Ankara expressing HIV-1 antigens.The immunoregulatory properties of oncolytic myxoma virus and their implications in therapeutics.
P2860
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P2860
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@ast
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@en
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@en-gb
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@nl
type
label
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@ast
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@en
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@en-gb
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@nl
prefLabel
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@ast
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@en
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@en-gb
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@nl
P2093
P2860
P356
P1433
P1476
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
@en
P2093
Alexander E Aleshin
Boguslaw Stec
Chaofang Jin
Dayong Zhai
John C Reed
Mika Aoyagi
Robert C Liddington
P2860
P304
P356
10.1110/PS.062454707
P407
P577
2007-01-01T00:00:00Z