Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation
about
TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKLThe innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κBNuclear tumor necrosis factor receptor-associated factor 6 in lymphoid cells negatively regulates c-Myb-mediated transactivation through small ubiquitin-related modifier-1 modificationActivation of interferon regulatory factor 5 by site specific phosphorylationThe E3 ligase TRAF6 regulates Akt ubiquitination and activationDirect activation of protein kinases by unanchored polyubiquitin chainsEndotoxin tolerance impairs IL-1 receptor-associated kinase (IRAK) 4 and TGF-beta-activated kinase 1 activation, K63-linked polyubiquitination and assembly of IRAK1, TNF receptor-associated factor 6, and IkappaB kinase gamma and increases A20 expresEssential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signalingLys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activationTumor necrosis factor receptor-associated factor 6 is an intranuclear transcriptional coactivator in osteoclastsThe RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKLAtypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review seriesIdentification of a consensus site for TRAF6/p62 polyubiquitinationUbc13: the Lys63 ubiquitin chain building machineUbiquitin signaling in immune responsesUbiquitin in the activation and attenuation of innate antiviral immunityRoles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functionsTargeting the ubiquitin pathway for cancer treatmentModulation of Intestinal TLR4-Inflammatory Signaling Pathways by Probiotic Microorganisms: Lessons Learned from Lactobacillus jensenii TL2937Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20E2 interaction and dimerization in the crystal structure of TRAF6Structural Basis for the Lack of E2 Interaction in the RING Domain of TRAF2The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory responseRegulation of inflammatory and antiviral signaling by A20.Distinct ubiquitination cascades act on the peroxisomal targeting signal type 2 co-receptor Pex18p.DUBA: a deubiquitinase that regulates type I interferon productionBSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiationInterleukin-1 receptor-associated kinase 2- and protein kinase D1-dependent regulation of IRAK-monocyte expression by CpG DNAWwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent mannerNegative regulation of IL-17-mediated signaling and inflammation by the ubiquitin-specific protease USP25Crosstalk in NF-κB signaling pathwaysYOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κBUbiquitin lysine 63 chain forming ligases regulate apical dominance in Arabidopsis.TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.Dynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNFalpha-induced inflammatory responsesInositol polyphosphate multikinase promotes Toll-like receptor-induced inflammation by stabilizing TRAF6.Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation.Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88.Signaling to NF-kappaB: regulation by ubiquitination.The Expanding Significance of Inositol Polyphosphate Multikinase as a Signaling Hub.
P2860
Q21092160-D91DA9B4-E87B-46D2-AE56-B4DBE66E7DC0Q24294960-E56005E4-0545-40D8-9D5B-E1F818BAFA4DQ24304276-E89467CF-5A33-4BD6-AE0F-182F6EC7AA63Q24307504-E1C38C83-1DDA-4249-9C76-7E3466C1BCCCQ24310343-6066D52C-0981-4409-A1C8-74461A5799CDQ24324679-68363D61-66CE-402C-9C18-0306E03BDE1AQ24336505-177D7480-AE31-4F9A-9BEE-BC679A584EF8Q24337661-B590F8A5-765C-498D-8C8F-617A56F76577Q24641992-EB10C45B-7310-4FF1-A384-88509088F39DQ24651323-7761D041-C0DD-4721-8F52-2559A61A4C92Q24654977-EDDAEAC5-72E2-4107-B715-9EA0967CC717Q24655287-4217D904-26B0-4757-8769-796DADBE3D31Q24657175-C95B5114-540A-4A47-9BD3-11683C522466Q26739716-CA7A8B7E-05AC-48D5-A4D7-4B616AFB50DEQ26751376-8CB5DAFE-AD1D-4CD4-92C8-A02E601ADCBFQ26771789-242C8CED-08A5-45A6-9E18-EF194974246DQ26853280-C67F9F1A-EC83-4754-A83B-2C046EAC713BQ26866185-8EA8EA05-FFFD-4841-B482-81D1CFDDAE77Q26992250-F6BADBB5-503C-4326-8C93-25F412FCBB42Q27649460-E7C7DBF6-BCA4-4A3E-9BE4-73F6AA26E514Q27655601-3B9A295B-1E28-42ED-A132-0FC532A4BF5EQ27657715-91418D4D-4258-4B61-B779-77EBCB5D5BECQ27677993-268AF628-0F98-444E-86B6-91A060DF3117Q27690854-B3A67082-E6F7-4D88-B540-7F32F83F0FA9Q27937595-39704051-F812-45C5-80B7-007B8BA7697FQ28118215-087E222B-7BA6-4721-ABB8-F990A7735DB5Q28282926-ECD88C9D-C856-499C-8A40-31568721AF9DQ28482485-8E5B9199-6D5E-4E5F-B2FD-F46A826E7821Q28585636-4E512F2D-B696-4287-991F-C56474C067E2Q28588560-709C5EBF-6E00-41ED-8085-3C5493D2DC38Q29617418-00CE7D7E-3454-406F-BFB3-BC2C31323D17Q30361285-24274B1D-9F75-4215-99D7-14909F642893Q33344184-07007B24-4D79-4E20-B1C9-EAD4AD9E1294Q33455769-63A723D2-4812-4FF6-9527-DAC05390C4E9Q33585802-9079CBE8-036D-41DC-AB3A-A634F79AD7C9Q33590960-1C912CF1-ABFD-424E-9943-8BF02CA931ECQ33648347-F04BE4F1-9C38-4223-9940-5726CC2B7CB6Q33683266-376486BB-BEFC-450E-987A-88D5E4BA4422Q33693806-11F64AF5-1F80-4712-9C82-08C1831674C0Q33775102-097ECC3F-869B-4382-97E6-60E5224F529F
P2860
Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@ast
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@en
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@en-gb
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@nl
type
label
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@ast
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@en
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@en-gb
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@nl
prefLabel
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@ast
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@en
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@en-gb
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@nl
P2093
P2860
P921
P3181
P356
P1476
Site-specific Lys-63-linked tu ...... of I kappa B kinase activation
@en
P2093
Alejandro D Campos
Arnaud Besse
Betty Lamothe
Bryant G Darnay
William K Webster
P2860
P304
P3181
P356
10.1074/JBC.M609503200
P407
P577
2007-02-09T00:00:00Z