ER stress differentially regulates the stabilities of ERAD ubiquitin ligases and their substrates
about
Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.The Unfolded Protein Response, Degradation from Endoplasmic Reticulum and CancerFamilial prion protein mutants inhibit Hrd1-mediated retrotranslocation of misfolded proteins by depleting misfolded protein sensor BiP.TRIM13 (RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NF Kappa B pathway and proteasome activity.Disruption of crosstalk between the fatty acid synthesis and proteasome pathways enhances unfolded protein response signaling and cell deathReal-time imaging of sodium glucose transporter (SGLT1) trafficking and activity in single cellsERAD ubiquitin ligases: multifunctional tools for protein quality control and waste disposal in the endoplasmic reticulum.Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein.Role of glycoprotein 78 and cidec in hepatic steatosisMicrobial biotransformation of DON: molecular basis for reduced toxicity.Gp78 E3 Ubiquitin Ligase: Essential Functions and Contributions in Proteostasis.Characterization of an ERAD pathway for nonglycosylated BiP substrates, which require Herp.Regulation of VCP/p97 demonstrates the critical balance between cell death and epithelial-mesenchymal transition (EMT) downstream of ER stress.HRD1-mediated ERAD tuning of ER-bound E2 is conserved between plants and mammals.
P2860
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P2860
ER stress differentially regulates the stabilities of ERAD ubiquitin ligases and their substrates
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
ER stress differentially regul ...... n ligases and their substrates
@ast
ER stress differentially regul ...... n ligases and their substrates
@en
ER stress differentially regul ...... n ligases and their substrates
@en-gb
ER stress differentially regul ...... n ligases and their substrates
@nl
type
label
ER stress differentially regul ...... n ligases and their substrates
@ast
ER stress differentially regul ...... n ligases and their substrates
@en
ER stress differentially regul ...... n ligases and their substrates
@en-gb
ER stress differentially regul ...... n ligases and their substrates
@nl
prefLabel
ER stress differentially regul ...... n ligases and their substrates
@ast
ER stress differentially regul ...... n ligases and their substrates
@en
ER stress differentially regul ...... n ligases and their substrates
@en-gb
ER stress differentially regul ...... n ligases and their substrates
@nl
P2093
P3181
P1476
ER stress differentially regul ...... n ligases and their substrates
@en
P2093
Andria Apostolou
Howard Doong
Shengyun Fang
Yuxian Shen
P304
P3181
P356
10.1016/J.BBRC.2006.11.121
P407
P50
P577
2006-12-04T00:00:00Z