Structure of a human carcinogen-converting enzyme, SULT1A1. Structural and kinetic implications of substrate inhibition
about
Structural and chemical profiling of the human cytosolic sulfotransferasesThe structure of human SULT1A1 crystallized with estradiol. An insight into active site plasticity and substrate inhibition with multi-ring substratesA homotropic two-state model and auto-antagonismPhylogenomic approaches to common problems encountered in the analysis of low copy repeats: the sulfotransferase 1A gene family exampleIn vitro inhibition of human hepatic and cDNA-expressed sulfotransferase activity with 3-hydroxybenzo[a]pyrene by polychlorobiphenylols.Predictive biomarkers in precision medicine and drug development against lung cancerThe structural biology of oestrogen metabolismSulfotransferase 1A1 Substrate Selectivity: A Molecular Clamp MechanismCrystal structure of StaL, a glycopeptide antibiotic sulfotransferase from Streptomyces toyocaensisCrystal structure of mSULT1D1, a mouse catecholamine sulfotransferaseThe Molecular Basis for the Broad Substrate Specificity of Human Sulfotransferase 1A1Mimicking of Estradiol Binding by Flame Retardants and Their Metabolites: A Crystallographic AnalysisStructure-Based Mutational Studies of Substrate Inhibition of Betaine Aldehyde Dehydrogenase BetB from Staphylococcus aureusInhibition of human phenol and estrogen sulfotransferase by certain non-steroidal anti-inflammatory agentsIn silico mechanistic profiling to probe small molecule binding to sulfotransferasesGenetic diversity and function in the human cytosolic sulfotransferases.A versatile polyacrylamide gel electrophoresis based sulfotransferase assay.Specific estrogen sulfotransferase (SULT1E1) substrates and molecular imaging probe candidates.Bioactivation of the human carcinogen aristolochic acidParadigms of sulfotransferase catalysis: the mechanism of SULT2A1.Substrate inhibition in human hydroxysteroid sulfotransferase SULT2A1: studies on the formation of catalytically non-productive enzyme complexesDrug targets in mycobacterial sulfur metabolism.New targets and inhibitors of mycobacterial sulfur metabolism.The allosteric binding sites of sulfotransferase 1A1.Expression of sulfotransferase SULT1A1 in cancer cells predicts susceptibility to the novel anticancer agent NSC-743380In silico pharmacology for drug discovery: applications to targets and beyondPotent inhibition of human sulfotransferase 1A1 by 17α-ethinylestradiol: role of 3'-phosphoadenosine 5'-phosphosulfate binding and structural rearrangements in regulating inhibition and activityRegioselective sulfation and glucuronidation of phenolics: insights into the structural basis.Human sulfotransferases and their role in chemical metabolism.RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.Sulfation of ractopamine and salbutamol by the human cytosolic sulfotransferases.Computational prediction of human drug metabolism.Design and Interpretation of Human Sulfotransferase 1A1 Assays.Sulphation of acetaminophen by the human cytosolic sulfotransferases: a systematic analysis.Inhibition of thyroid hormone sulfotransferase activity by brominated flame retardants and halogenated phenolics.Chlorinated biphenyl quinones and phenyl-2,5-benzoquinone differentially modify the catalytic activity of human hydroxysteroid sulfotransferase hSULT2A1.Expression and functional activities of selected sulfotransferase isoforms in BeWo cells and primary cytotrophoblast cells.para-Nitrophenyl sulfate activation of human sulfotransferase 1A1 is consistent with intercepting the E[middle dot]PAP complex and reformation of E[middle dot]PAPS.Structure, dynamics and selectivity in the sulfotransferase family.From sequence and structure of sulfotransferases and dihydropyrimidinases to an understanding of their mechanisms of action and function.
P2860
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P2860
Structure of a human carcinogen-converting enzyme, SULT1A1. Structural and kinetic implications of substrate inhibition
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Structure of a human carcinoge ...... ations of substrate inhibition
@ast
Structure of a human carcinoge ...... ations of substrate inhibition
@en
Structure of a human carcinoge ...... ations of substrate inhibition
@en-gb
Structure of a human carcinoge ...... ations of substrate inhibition
@nl
type
label
Structure of a human carcinoge ...... ations of substrate inhibition
@ast
Structure of a human carcinoge ...... ations of substrate inhibition
@en
Structure of a human carcinoge ...... ations of substrate inhibition
@en-gb
Structure of a human carcinoge ...... ations of substrate inhibition
@nl
prefLabel
Structure of a human carcinoge ...... ations of substrate inhibition
@ast
Structure of a human carcinoge ...... ations of substrate inhibition
@en
Structure of a human carcinoge ...... ations of substrate inhibition
@en-gb
Structure of a human carcinoge ...... ations of substrate inhibition
@nl
P2093
P2860
P356
P1476
Structure of a human carcinoge ...... ations of substrate inhibition
@en
P2093
Amanda C Barnett
Catherine F Latham
Jennifer L Martin
Michael E McManus
Michael Tresillian
Nancy E Liyou
Niranjali U Gamage
Ronald G Duggleby
P2860
P304
P356
10.1074/JBC.M207246200
P407
P577
2003-02-28T00:00:00Z