Regioselective sulfation and glucuronidation of phenolics: insights into the structural basis.
about
Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosaAbsolute quantification of UGT1A1 in various tissues and cell lines using isotope label-free UPLC-MS/MS method determines its turnover number and correlates with its glucuronidation activities.Mutual interactions between flavonoids and enzymatic and transporter elements responsible for flavonoid disposition via phase II metabolic pathways.Identification and pharmacokinetics of multiple potential bioactive constituents after oral administration of radix astragali on cyclophosphamide-induced immunosuppression in Balb/c mice.Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity.Pharmacokinetics, metabolism, and in vivo efficacy of the antimalarial natural product bromophycolide AMutual regioselective inhibition of human UGT1A1-mediated glucuronidation of four flavonoidsUnderstanding substrate selectivity of human UDP-glucuronosyltransferases through QSAR modeling and analysis of homologous enzymes.Crystal structures of human sulfotransferases: insights into the mechanisms of action and substrate selectivity.Regioselective biotransformation of CNS drugs and its clinical impact on adverse drug reactions.Gender-dependent differences in uridine 5'-diphospho-glucuronosyltransferase have implications in metabolism and clearance of xenobiotics.Flavonoid interactions during digestion, absorption, distribution and metabolism: a sequential structure-activity/property relationship-based approach in the study of bioavailability and bioactivity.Dietary flavonoid aglycones and their glycosides: Which show better biological significance?Direct and indirect measurements of enhanced phenolic bioavailability from litchi pericarp procyanidins by Lactobacillus casei-01.Antiproliferative activity of the ellagic acid-derived gut microbiota isourolithin A and comparison with its urolithin A isomer: the role of cell metabolism.In Vitro Glucuronidation of Wushanicaritin by Liver Microsomes, Intestine Microsomes and Expressed Human UDP-Glucuronosyltransferase Enzymes.Regioselective glucuronidation of gingerols by human liver microsomes and expressed UDP-glucuronosyltransferase enzymes: reaction kinetics and activity correlation analyses for UGT1A9 and UGT2B7.In Vitro Glucuronidation and Sulfation of ε-Viniferin, a Resveratrol Dimer, in Humans and Rats.Chemical inhibition and stable knock-down of efflux transporters leads to reduced glucuronidation of wushanicaritin in UGT1A1-overexpressing HeLa cells: the role of breast cancer resistance protein (BCRP) and multidrug resistance-associated proteinsAntihyperglycemic, hypolipidemic, hepatoprotective and antioxidative effects of dietary clove (Szyzgium aromaticum) bud powder in a high-fat diet/streptozotocin-induced diabetes rat model.Cardiovascular and Antiobesity Effects of Resveratrol Mediated through the Gut Microbiota.3D-QSAR studies on UDP-glucuronosyltransferase 2B7 substrates using the pharmacophore and VolSurf approaches.Phenolic sulfates as new and highly abundant metabolites in human plasma after ingestion of a mixed berry fruit purée.
P2860
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P2860
Regioselective sulfation and glucuronidation of phenolics: insights into the structural basis.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Regioselective sulfation and g ...... hts into the structural basis.
@ast
Regioselective sulfation and g ...... hts into the structural basis.
@en
type
label
Regioselective sulfation and g ...... hts into the structural basis.
@ast
Regioselective sulfation and g ...... hts into the structural basis.
@en
prefLabel
Regioselective sulfation and g ...... hts into the structural basis.
@ast
Regioselective sulfation and g ...... hts into the structural basis.
@en
P2093
P2860
P1476
Regioselective sulfation and g ...... hts into the structural basis.
@en
P2093
Baojian Wu
Shengnan Meng
Sumit Basu
Xiaoqiang Wang
P2860
P304
P356
10.2174/138920011797470100
P407
P577
2011-11-01T00:00:00Z