A novel variant of human Grb7 is associated with invasive esophageal carcinoma
about
Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptorInteraction of the Grb7 adapter protein with Rnd1, a new member of the Rho familyRole of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migrationIdentification of a novel human tankyrase through its interaction with the adaptor protein Grb14Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulationThe adaptor Grb7 is a novel calmodulin-binding protein: functional implications of the interaction of calmodulin with Grb7Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesisTyrosine kinase signalling in breast cancer: modulation of tyrosine kinase signalling in human breast cancer through altered expression of signalling intermediates.Localization of endogenous Grb10 to the mitochondria and its interaction with the mitochondrial-associated Raf-1 poolAssociation of focal adhesion kinase with Grb7 and its role in cell migrationEvidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functionsIdentification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptorIdentification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7.Growth factor receptor-bound protein-7 (Grb7) as a prognostic marker and therapeutic target in breast cancer.Kappa opioid receptor contributes to EGF-stimulated neurite extension in developmentGrb7 and Filamin-a associate and are colocalized to cell membrane ruffles upon EGF stimulation.Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14.The cell migration protein Grb7 associates with transcriptional regulator FHL2 in a Grb7 phosphorylation-dependent manner.An Integrative Analysis to Identify Driver Genes in Esophageal Squamous Cell CarcinomaGrb10 and Grb14: enigmatic regulators of insulin action--and more?Adapter protein connections: the MRL and Grb7 protein families.Combination treatment with Grb7 peptide and Doxorubicin or Trastuzumab (Herceptin) results in cooperative cell growth inhibition in breast cancer cells.Dissecting GRB7-mediated signals for proliferation and migration in HER2 overexpressing breast tumor cells: GTP-ase rules.Genomic organization and control of the grb7 gene family.Calmodulin regulates the translocation of Grb7 into the nucleus.RNA-seq analysis of the whole transcriptome of MDA-MB-231 mammary carcinoma cells exposed to the antimetastatic drug NAMI-A.In vitro antiproliferative effect of trastuzumab (Herceptin(®)) combined with cetuximab (Erbitux(®)) in a model of human non-small cell lung cancer expressing EGFR and HER2.Context-dependent role of Grb7 in HER2+ve and triple-negative breast cancer cell lines.Grb7 and Hax1 may colocalize partially to mitochondria in EGF-treated SKBR3 cells and their interaction can affect Caspase3 cleavage of Hax1Dimerization in the Grb7 protein.Tie2 vascular endothelial receptor expression and function in hepatocellular carcinoma.Inhibition of FGF receptor signalling in Xenopus oocytes: differential effect of Grb7, Grb10 and Grb14.The adaptors Grb10 and Grb14 are calmodulin-binding proteins.EST comparison indicates 38% of human mRNAs contain possible alternative splice forms.Specific peptide ligand for Grb7 signal transduction protein and pancreatic cancer metastasis.Precision medicine based on surgical oncology in the era of genome-scale analysis and genome editing technology.
P2860
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P2860
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@ast
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@en
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@en-gb
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@nl
type
label
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@ast
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@en
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@en-gb
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@nl
prefLabel
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@ast
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@en
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@en-gb
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@nl
P2093
P2860
P356
P1476
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
@en
P2093
K Sugimachi
T Akiyoshi
P2860
P356
10.1172/JCI2921
P407
P577
1998-08-15T00:00:00Z