Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands
about
Orphan nuclear receptors and the regulation of nutrient metabolism: understanding obesityRegulation of the cytosolic sulfotransferases by nuclear receptorsThe therapeutic potential of RORγ modulators in the treatment of human diseaseStructural Basis of Digoxin That Antagonizes ROR t Receptor Activity and Suppresses Th17 Cell Differentiation and Interleukin (IL)-17 ProductionCharacterization of the core mammalian clock component, NPAS2, as a REV-ERBalpha/RORalpha target geneSterol metabolism controls T(H)17 differentiation by generating endogenous RORγ agonistsTherapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of AutismAdipogenesis and insulin sensitivity in obesity are regulated by retinoid-related orphan receptor gammaInhibition of intestinal bile acid transporter Slc10a2 improves triglyceride metabolism and normalizes elevated plasma glucose levels in miceSeven perspectives on GPCR H/D-exchange proteomics methodsNuclear receptors as drug targets for metabolic disease.Oxysterols and their cellular effectors.RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D.Development of an HTS-compatible assay for discovery of RORα modulators using AlphaScreen® technology.Regulation of FGF21 expression and secretion by retinoic acid receptor-related orphan receptor alpha.A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol)Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation.Ligand regulation of retinoic acid receptor-related orphan receptors: implications for development of novel therapeuticsGenome-wide interrogation of hepatic FXR reveals an asymmetric IR-1 motif and synergy with LRH-1.Regulation of expression of citrate synthase by the retinoic acid receptor-related orphan receptor α (RORα)Regulation of p53 stability and apoptosis by a ROR agonistAction of RORs and their ligands in (patho)physiology.Regulation of the human hydroxysteroid sulfotransferase (SULT2A1) by RORα and RORγ and its potential relevance to human liver diseases.REV-ERB and ROR nuclear receptors as drug targets.Endogenous ligands for nuclear receptors: digging deeper.Identification of SR1078, a synthetic agonist for the orphan nuclear receptors RORα and RORγ.Small molecule amides as potent ROR-γ selective modulators.Nuclear receptors linking circadian rhythms and cardiometabolic control.Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonistThe identification of naturally occurring neoruscogenin as a bioavailable, potent, and high-affinity agonist of the nuclear receptor RORα (NR1F1).Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactionsRetinoic acid-related orphan receptor γ directly regulates neuronal PAS domain protein 2 transcription in vivo.Identification of natural RORγ ligands that regulate the development of lymphoid cellsTranscriptional profiling reveals a role for RORalpha in regulating gene expression in obesity-associated inflammation and hepatic steatosis.The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis.Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligandTargeting orphan nuclear receptors for treatment of metabolic diseases and autoimmunityIdentification of SR2211: a potent synthetic RORγ-selective modulator.RORα and 25-Hydroxycholesterol Crosstalk Regulates Lipid Droplet Homeostasis in MacrophagesLess is More: Membrane Protein Digestion Beyond Urea-Trypsin Solution for Next-level Proteomics
P2860
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P2860
Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@ast
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@en
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@en-gb
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@nl
type
label
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@ast
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@en
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@en-gb
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@nl
prefLabel
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@ast
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@en
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@en-gb
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@nl
P2093
P2860
P921
P3181
P356
P1476
Modulation of retinoic acid re ...... by 7-oxygenated sterol ligands
@en
P2093
Christine Crumbley
Keith R Stayrook
Laura A Solt
Leah M Helvering
Michael J Chalmers
Naresh Kumar
Patrick R Griffin
Ruben D Garcia-Ordonez
Scott Novick
Timothy I Richardson
P2860
P304
P3181
P356
10.1074/JBC.M109.080614
P407
P577
2009-12-04T00:00:00Z