about
TM6SF2 E167K Variant, a Novel Genetic Susceptibility Variant, Contributing to Nonalcoholic Fatty Liver DiseaseGenetic Factors in the Pathogenesis of Nonalcoholic Fatty Liver and SteatohepatitisHepatic lipid droplet biology: Getting to the root of fatty liverMetabolic profiling reveals that PNPLA3 induces widespread effects on metabolism beyond triacylglycerol remodeling in Huh-7 hepatoma cells.MBOAT7 rs641738 variant and hepatocellular carcinoma in non-cirrhotic individuals.Interaction between PNPLA3 I148M variant and age at infection in determining fibrosis progression in chronic hepatitis C.The rs738409 (I148M) variant of the PNPLA3 gene and cirrhosis: a meta-analysisFrom whole body to cellular models of hepatic triglyceride metabolism: man has got to know his limitationsIdentification of eQTLs for hepatic Xbp1s and Socs3 gene expression in mice fed a high-fat, high-caloric diet.PNPLA3 genetic variation in alcoholic steatosis and liver disease progression.The Impact of PNPLA3 rs738409 Genetic Polymorphism and Weight Gain ≥10 kg after Age 20 on Non-Alcoholic Fatty Liver Disease in Non-Obese Japanese IndividualsPathophysiology of lipid droplet proteins in liver diseases.The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent.Overexpression of variant PNPLA3 gene at I148M position causes malignant transformation of hepatocytes via IL-6-JAK2/STAT3 pathway in low dose free fatty acid exposure: a laboratory investigation in vitro and in vivo.PNPLA3 Expression Is Related to Liver Steatosis in Morbidly Obese Women with Non-Alcoholic Fatty Liver Disease.ATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cellsPharmacogenomic and personalized approaches to tackle nonalcoholic fatty liver disease.Nonalcoholic fatty liver disease: cause or consequence of type 2 diabetes?Shifts in dietary carbohydrate-lipid exposure regulate expression of the non-alcoholic fatty liver disease-associated gene PNPLA3/adiponutrin in mouse liver and HepG2 human liver cells.Lipid droplets and liver disease: from basic biology to clinical implications.Binge alcohol alters PNPLA3 levels in liver through epigenetic mechanism involving histone H3 acetylation.Combination of PNPLA3 and TLL1 polymorphism can predict advanced fibrosis in Japanese patients with nonalcoholic fatty liver disease.Transmembrane 6 superfamily member 2 gene E167K variant impacts on steatosis and liver damage in chronic hepatitis C patients.Identification of deleterious rare variants in MTTP, PNPLA3, and TM6SF2 in Japanese males and association studies with NAFLD.Non-alcoholic Fatty Liver Disease in Lean Subjects: Characteristics and Implications.The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation.In vitro cellular models of human hepatic fatty acid metabolism: differences between Huh7 and HepG2 cell lines in human and fetal bovine culturing serum.Triglyceride Metabolism in the Liver.Mutant PNPLA3 I148M protein as pharmacological target for liver disease.Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease.Patatin-like phospholipase domain-containing protein 3 promotes transfer of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets.The rs2294918 E434K variant modulates patatin-like phospholipase domain-containing 3 expression and liver damage.Coding variants in PNPLA3 and TM6SF2 are risk factors for hepatic steatosis and elevated serum alanine aminotransferases caused by a glucagon receptor antagonist.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@ast
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@en
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@en-gb
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@nl
type
label
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@ast
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@en
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@en-gb
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@nl
prefLabel
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@ast
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@en
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@en-gb
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
PNPLA3 mediates hepatocyte triacylglycerol remodeling
@en
P2093
Hanna Ruhanen
Hannele Yki-Järvinen
Julia Perttilä
Reijo Käkelä
P2860
P304
P3181
P356
10.1194/JLR.M046607
P407
P577
2014-04-01T00:00:00Z