Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk
about
Recoupling the cardiac nitric oxide synthases: tetrahydrobiopterin synthesis and recyclingLow-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration.Oxidative risk for atherothrombotic cardiovascular disease.Exploring epistatic relationships of NO biosynthesis pathway genes in susceptibility to CHD.Tetrahydrobiopterin in cardiovascular health and disease.Tetrahydrobiopterin, superoxide, and vascular dysfunction.AKAP10 (I646V) functional polymorphism predicts heart rate and heart rate variability in apparently healthy, middle-aged European-Americans.GTP cyclohydrolase I gene polymorphisms are associated with endothelial dysfunction and oxidative stress in patients with type 2 diabetes mellitus.Genetic covariance between gamma-glutamyl transpeptidase and fatty liver risk factors: role of beta2-adrenergic receptor genetic variation in twins.A GCH1 haplotype confers sex-specific susceptibility to pain crises and altered endothelial function in adults with sickle cell anemia.Differential effects of eNOS uncoupling on conduit and small arteries in GTP-cyclohydrolase I-deficient hph-1 mice.GCH1, BH4 and painRegulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.Isoflurane favorably modulates guanosine triphosphate cyclohydrolase-1 and endothelial nitric oxide synthase during myocardial ischemia and reperfusion injury in rats.Nucleotide Variants of the BH4 Biosynthesis Pathway Gene GCH1 and the Risk of Orofacial Clefts.Hereditary determinants of human hypertension: strategies in the setting of genetic complexity.Vascular protection by tetrahydrobiopterin: progress and therapeutic prospectsGenetic mutations that prevent pain: implications for future pain medication.GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial functionPeroxynitrite-dependent zinc release and inactivation of guanosine 5'-triphosphate cyclohydrolase 1 instigate its ubiquitination in diabetes.Do genetic predictors of pain sensitivity associate with persistent widespread pain?Neuropeptide Y(1) Receptor NPY1R discovery of naturally occurring human genetic variants governing gene expression in cella as well as pleiotropic effects on autonomic activity and blood pressure in vivo.Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid (microrna) motif in the 3'-UTR of cytochrome b561 [corrected]A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice.Polymorphisms of genes in nitric oxide-forming pathway associated with ischemic stroke in Chinese Han population.Genetic variability of pain perception and treatment--clinical pharmacological implications.Oxidative stress and endothelial dysfunction in hypertension.Modulating endothelial nitric oxide synthase: a new cardiovascular therapeutic strategy.Analgesia by inhibiting tetrahydrobiopterin synthesis.Pharmacogenetics of pain and analgesia.Arginine and nitric oxide synthase: regulatory mechanisms and cardiovascular aspects.Effect of huanglian jiedu decoction on thoracic aorta gene expression in spontaneous hypertensive rats.Acute inhibition of guanosine triphosphate cyclohydrolase 1 uncouples endothelial nitric oxide synthase and elevates blood pressure.Complex trait genetics the role of mechanistic "intermediate phenotypes" and candidate genetic loci.Heritability of cardiac vagal control in 24-h heart rate variability recordings: influence of ceiling effects at low heart rates.Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer's disease pathogenesis.Development of an AmpliSeq Panel for Next-Generation Sequencing of a Set of Genetic Predictors of Persisting Pain
P2860
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P2860
Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Discovery of common human gene ...... ivity, and cardiovascular risk
@ast
Discovery of common human gene ...... ivity, and cardiovascular risk
@en
Discovery of common human gene ...... ivity, and cardiovascular risk
@en-gb
Discovery of common human gene ...... ivity, and cardiovascular risk
@nl
type
label
Discovery of common human gene ...... ivity, and cardiovascular risk
@ast
Discovery of common human gene ...... ivity, and cardiovascular risk
@en
Discovery of common human gene ...... ivity, and cardiovascular risk
@en-gb
Discovery of common human gene ...... ivity, and cardiovascular risk
@nl
prefLabel
Discovery of common human gene ...... ivity, and cardiovascular risk
@ast
Discovery of common human gene ...... ivity, and cardiovascular risk
@en
Discovery of common human gene ...... ivity, and cardiovascular risk
@en-gb
Discovery of common human gene ...... ivity, and cardiovascular risk
@nl
P2093
P2860
P50
P921
P356
P1476
Discovery of common human gene ...... ivity, and cardiovascular risk
@en
P2093
Brinda K Rana
Daniel T O'Connor
Douglas W Smith
Fangwen Rao
Kuixing Zhang
Lian Zhang
Madhusudan Das
Michael G Ziegler
Nicholas J Schork
Srikrishna Khandrika
P2860
P304
P356
10.1172/JCI31093
P407
P577
2007-09-01T00:00:00Z