What the Myddosome structure tells us about the initiation of innate immunity
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IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNAWDFY1 mediates TLR3/4 signaling by recruiting TRIFThe structural biology of Toll-like receptorsIdentifying novel spatiotemporal regulators of innate immunityContribution of toll-like receptor signaling pathways to breast tumorigenesis and treatmentIntracellular nucleic acid sensors and autoimmunityDeletion of the vaccinia virus gene A46R, encoding for an inhibitor of TLR signalling, is an effective approach to enhance the immunogenicity in mice of the HIV/AIDS vaccine candidate NYVAC-CCrystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protectionStructures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signalingStructural basis for the prion-like MAVS filaments in antiviral innate immunityIn silico approach to inhibition of signaling pathways of Toll-like receptors 2 and 4 by ST2LMycobacteria counteract a TLR-mediated nitrosative defense mechanism in a zebrafish infection modelA promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction.Membrane targeting of TIRAP is negatively regulated by phosphorylation in its phosphoinositide-binding motif.MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases.Inhibition of Myeloid Differentiation Factor 88 Reduces Human and Mouse T-Cell Interleukin-17 and IFNγ Production and Ameliorates Experimental Autoimmune Encephalomyelitis Induced in MiceRNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events.A coding IRAK2 protein variant compromises Toll-like receptor (TLR) signaling and is associated with colorectal cancer survival.A Staphylococcus aureus TIR domain protein virulence factor blocks TLR2-mediated NF-κB signaling.Real-time imaging and genetic dissection of host-microbe interactions in zebrafish.The TLR4 D299G and T399I SNPs are constitutively active to up-regulate expression of Trif-dependent genes.TRAM is required for TLR2 endosomal signaling to type I IFN inductionChronic inflammation in cancer development.Poxviral protein A46 antagonizes Toll-like receptor 4 signaling by targeting BB loop motifs in Toll-IL-1 receptor adaptor proteins to disrupt receptor:adaptor interactionsSystems biology approaches to toll-like receptor signaling.Toll-like Receptors in the Vascular System: Sensing the Dangers Within.Shedding of the tumor necrosis factor (TNF) receptor from the surface of hepatocytes during sepsis limits inflammation through cGMP signaling.Cytokines in radiobiological responses: a review.Toll-like receptor polymorphisms, inflammatory and infectious diseases, allergies, and cancer.Inherited human IRAK-1 deficiency selectively impairs TLR signaling in fibroblastsPPAR-γ/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsisStructure-Activity Relationship in TLR4 Mutations: Atomistic Molecular Dynamics Simulations and Residue Interaction Network Analysis.Toll-like receptors are key players in neurodegeneration.Similar Structures but Different Roles - An Updated Perspective on TLR Structures.Intracellular sensors of extracellular bacteria.Different dimerisation mode for TLR4 upon endosomal acidification?Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3KStructural basis of innate immune recognition of viral RNA.Mal, more than a bridge to MyD88.Advances in Toll-like receptor biology: Modes of activation by diverse stimuli.
P2860
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P2860
What the Myddosome structure tells us about the initiation of innate immunity
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2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
What the Myddosome structure tells us about the initiation of innate immunity
@ast
What the Myddosome structure tells us about the initiation of innate immunity
@en
What the Myddosome structure tells us about the initiation of innate immunity
@en-gb
What the Myddosome structure tells us about the initiation of innate immunity
@nl
type
label
What the Myddosome structure tells us about the initiation of innate immunity
@ast
What the Myddosome structure tells us about the initiation of innate immunity
@en
What the Myddosome structure tells us about the initiation of innate immunity
@en-gb
What the Myddosome structure tells us about the initiation of innate immunity
@nl
prefLabel
What the Myddosome structure tells us about the initiation of innate immunity
@ast
What the Myddosome structure tells us about the initiation of innate immunity
@en
What the Myddosome structure tells us about the initiation of innate immunity
@en-gb
What the Myddosome structure tells us about the initiation of innate immunity
@nl
P356
P1433
P1476
What the Myddosome structure tells us about the initiation of innate immunity
@en
P2093
Nicholas J Gay
P304
P356
10.1016/J.IT.2010.12.005
P407
P577
2011-01-25T00:00:00Z