A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28
about
Protein kinase C signaling and cell cycle regulationDynamic Regulation of TCR-Microclusters and the Microsynapse for T Cell ActivationCell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand RecognitionTCR Signaling in T Cell MemoryPKC-Theta in Regulatory and Effector T-cell FunctionsThe Novel PKCθ from Benchtop to ClinicPKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytesProtein kinase C in the immune system: from signalling to chromatin regulationThe lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cellsChemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cellsClustering of CARMA1 through SH3-GUK domain interactions is required for its activation of NF-κB signalling.Quantitative analysis by surface plasmon resonance of CD28 interaction with cytoplasmic adaptor molecules Grb2, Gads and p85 PI3K.Murine regulatory T cells differ from conventional T cells in resisting the CTLA-4 reversal of TCR stop-signal.Protein kinase C-η controls CTLA-4-mediated regulatory T cell function.TCR Microclusters pre-exist and contain molecules necessary for TCR signal transduction.Primary murine CD4+ T cells fail to acquire the ability to produce effector cytokines when active Ras is present during Th1/Th2 differentiation.T cell receptor signaling can directly enhance the avidity of CD28 ligand binding.The variable hinge region of novel PKCs determines localization to distinct regions of the immunological synapseCombinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor.Regulation of the PKCθ-NF-κB Axis in T Lymphocytes by the Tumor Necrosis Factor Receptor Family Member OX40Regulation of PKC-θ function by phosphorylation in T cell receptor signaling.From lipid second messengers to molecular motors: microtubule-organizing center reorientation in T cellseNOS S-nitrosylates β-actin on Cys374 and regulates PKC-θ at the immune synapse by impairing actin binding to profilin-1.Protein kinase C theta is dispensable for suppression mediated by CD25+CD4+ regulatory T cells.A phospholipase C-γ1-independent, RasGRP1-ERK-dependent pathway drives lymphoproliferative disease in linker for activation of T cells-Y136F mutant mice.The emerging role of protein kinase Cθ in cytoskeletal signaling.TNFR-associated factor 6 regulates TCR signaling via interaction with and modification of LAT adapterIn and out of the bull's eye: protein kinase Cs in the immunological synapse.Role of diacylglycerol kinases in T cell development and function.A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1.Lipid-based patterning of the immunological synapseThe scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells.Ras and extracellular signal-regulated kinase signaling in thymocytes and T cells.The yin and yang of protein kinase C-theta (PKCθ): a novel drug target for selective immunosuppression.The role of protein kinase cη in T cell biologyProtein kinase C inhibitors for immune disorders.Integrative biology of T cell activation.PKCθ-regulated signalling in health and disease.Redundant and specialized roles for diacylglycerol kinases α and ζ in the control of T cell functions.CD28 Costimulation: From Mechanism to Therapy.
P2860
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P2860
A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A motif in the V3 domain of th ...... ells via association with CD28
@ast
A motif in the V3 domain of th ...... ells via association with CD28
@en
A motif in the V3 domain of th ...... ells via association with CD28
@en-gb
A motif in the V3 domain of th ...... ells via association with CD28
@nl
type
label
A motif in the V3 domain of th ...... ells via association with CD28
@ast
A motif in the V3 domain of th ...... ells via association with CD28
@en
A motif in the V3 domain of th ...... ells via association with CD28
@en-gb
A motif in the V3 domain of th ...... ells via association with CD28
@nl
prefLabel
A motif in the V3 domain of th ...... ells via association with CD28
@ast
A motif in the V3 domain of th ...... ells via association with CD28
@en
A motif in the V3 domain of th ...... ells via association with CD28
@en-gb
A motif in the V3 domain of th ...... ells via association with CD28
@nl
P2093
P2860
P3181
P356
P1433
P1476
A motif in the V3 domain of th ...... ells via association with CD28
@en
P2093
Amnon Altman
Ann J Canonigo-Balancio
Kok-Fai Kong
Noah Isakov
Tadashi Yokosuka
P2860
P2888
P304
P3181
P356
10.1038/NI.2120
P407
P577
2011-11-01T00:00:00Z
P5875
P6179
1035734252