Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses
about
A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28TCR Signaling in T Cell MemoryPKC-Theta in Regulatory and Effector T-cell FunctionsThe Role of PKC-θ in CD4+ T Cells and HIV Infection: To the Nucleus and Back AgainRole of T cell-nuclear factor κB in transplantationThe Novel PKCθ from Benchtop to ClinicEarly signaling events that underlie fate decisions of naive CD4(+) T cells toward distinct T-helper cell subsetsPKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytesProtein kinase C θ regulates the phenotype of murine CD4+ Th17 cellsIdentification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)Diacylglycerol Kinases in T Cell Tolerance and Effector FunctionProtein kinase C in the immune system: from signalling to chromatin regulationControl of T helper 2 cell function and allergic airway inflammation by PKCzetaAutoimmunity in primary T-cell immunodeficiencies.A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.Organization of proximal signal initiation at the TCR:CD3 complex.Protein kinase C theta is not essential for T-cell-mediated clearance of murine gammaherpesvirus 68.Regulatory T cells and Toll-like receptors: what is the missing link?T-cell-receptor-dependent signal intensity dominantly controls CD4(+) T cell polarization In Vivo.Protective Toxoplasma gondii-specific T-cell responses require T-cell-specific expression of protein kinase C-theta.Innate signals compensate for the absence of PKC-{theta} during in vivo CD8(+) T cell effector and memory responsesCritical role of novel Thr-219 autophosphorylation for the cellular function of PKCtheta in T lymphocytes.Protein kinase C θ deficiency increases resistance of C57BL/6J mice to Plasmodium berghei infection-induced cerebral malaria.The progesterone-induced blocking factor modulates the balance of PKC and intracellular Ca.Itk: the rheostat of the T cell response.Protein kinase C η is required for T cell activation and homeostatic proliferation.Impaired IL-4 and c-Maf expression and enhanced Th1-cell development in Vav1-deficient mice.CARMA1 controls Th2 cell-specific cytokine expression through regulating JunB and GATA3 transcription factors.Oral Administration of 4-Hydroxy-3-Methoxycinnamaldehyde Attenuates Atopic Dermatitis by Inhibiting T Cell and Keratinocyte ActivationOral Administration of p-Hydroxycinnamic Acid Attenuates Atopic Dermatitis by Downregulating Th1 and Th2 Cytokine Production and Keratinocyte Activation.Molecular and cellular pathogenesis of X-linked lymphoproliferative disease.TEC-family kinases: regulators of T-helper-cell differentiation.Chronic activation of the kinase IKKβ impairs T cell function and survival.Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.Dyslipidemia inhibits Toll-like receptor-induced activation of CD8alpha-negative dendritic cells and protective Th1 type immunityProtein kinase C theta is required for efficient induction of IL-10-secreting T cells.PKCzeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways.Protein kinase C theta is dispensable for suppression mediated by CD25+CD4+ regulatory T cells.A critical role for protein kinase C-theta-mediated T cell survival in cardiac allograft rejection.In and out of the bull's eye: protein kinase Cs in the immunological synapse.
P2860
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P2860
Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses
description
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Juli 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/07/19)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/07/19)
@nl
наукова стаття, опублікована в липні 2004
@uk
مقالة علمية (نشرت في 19-7-2004)
@ar
name
Protein kinase C theta is crit ...... ell but not Th1 cell responses
@ast
Protein kinase C theta is crit ...... ell but not Th1 cell responses
@en
Protein kinase C theta is crit ...... ell but not Th1 cell responses
@nl
type
label
Protein kinase C theta is crit ...... ell but not Th1 cell responses
@ast
Protein kinase C theta is crit ...... ell but not Th1 cell responses
@en
Protein kinase C theta is crit ...... ell but not Th1 cell responses
@nl
prefLabel
Protein kinase C theta is crit ...... ell but not Th1 cell responses
@ast
Protein kinase C theta is crit ...... ell but not Th1 cell responses
@en
Protein kinase C theta is crit ...... ell but not Th1 cell responses
@nl
P2093
P2860
P3181
P356
P1476
Protein kinase C theta is crit ...... ell but not Th1 cell responses
@en
P2093
Benjamin J. Marsland
Dan R. Littman
Gerald Späth
Timothy J. Soos
P2860
P304
P3181
P356
10.1084/JEM.20032229
P407
P50
P577
2004-07-19T00:00:00Z