Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms
about
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cellsSynthetic lethality in lung cancer and translation to clinical therapiesIdentifying core gene modules in glioblastoma based on multilayer factor-mediated dysfunctional regulatory networks through integrating multi-dimensional genomic data.APOSTL: An Interactive Galaxy Pipeline for Reproducible Analysis of Affinity Proteomics Data.Comparison of gene expression patterns across 12 tumor types identifies a cancer supercluster characterized by TP53 mutations and cell cycle defectsAnnotation of human cancers with EGFR signaling-associated protein complexes using proximity ligation assaysTarget Identification in Small Cell Lung Cancer via Integrated Phenotypic Screening and Activity-Based Protein ProfilingGli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer.Identification of Topological Network Modules in Perturbed Protein Interaction Networks.Coupling an EML4-ALK-centric interactome with RNA interference identifies sensitizers to ALK inhibitors.Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking.Building and exploring an integrated human kinase network: global organization and medical entry points.Exploiting Synthetic Lethality and Network Biology to Overcome EGFR Inhibitor Resistance in Lung Cancer.MET-GRB2 Signaling-Associated Complexes Correlate with Oncogenic MET Signaling and Sensitivity to MET Kinase Inhibitors.Deploying ibrutinib to lung cancer: another step in the quest towards drug repurposing.Transcriptionally inducible Pleckstrin homology-like domain family A member 1 attenuates ErbB receptor activity by inhibiting receptor oligomerization.CAR-T cells and combination therapies: What's next in the immunotherapy revolution?Correlation analysis of mesenchymal-epithelial transition factor protein and human epidermal growth receptor 2 protein expression in 1479 cases of lung adenocarcinoma in China.Aberrant expression of miR-21, miR-376c and miR-145 and their target host genes in Merkel cell polyomavirus-positive non-small cell lung cancer.Cell signaling heterogeneity is modulated by both cell-intrinsic and -extrinsic mechanisms: An integrated approach to understanding targeted therapy.Integrin β3 links therapy resistance and cancer stem cell properties.
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P2860
Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Perturbation of the mutated EG ...... ties and resistance mechanisms
@ast
Perturbation of the mutated EG ...... ties and resistance mechanisms
@en
Perturbation of the mutated EG ...... ties and resistance mechanisms
@en-gb
Perturbation of the mutated EG ...... ties and resistance mechanisms
@nl
type
label
Perturbation of the mutated EG ...... ties and resistance mechanisms
@ast
Perturbation of the mutated EG ...... ties and resistance mechanisms
@en
Perturbation of the mutated EG ...... ties and resistance mechanisms
@en-gb
Perturbation of the mutated EG ...... ties and resistance mechanisms
@nl
prefLabel
Perturbation of the mutated EG ...... ties and resistance mechanisms
@ast
Perturbation of the mutated EG ...... ties and resistance mechanisms
@en
Perturbation of the mutated EG ...... ties and resistance mechanisms
@en-gb
Perturbation of the mutated EG ...... ties and resistance mechanisms
@nl
P2093
P2860
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P3181
P356
P1476
Perturbation of the mutated EG ...... ties and resistance mechanisms
@en
P2093
Bhupendra Rawal
Eric B Haura
Georg Winter
Guolin Zhang
Isamu Okamoto
Jiannong Li
John Koomen
Keiryn Bennett
Lanxi Song
P2860
P3181
P356
10.1038/MSB.2013.61
P407
P577
2013-01-01T00:00:00Z