Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase - Wikidata - wikimedia - TriplyDB

Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase

Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase

http://www.wikidata.org/entity/Q24294831

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PTPN14 is required for the density-dependent control of YAP1 Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis The fate of chemoresistance in triple negative breast cancer (TNBC)The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes Temporal regulation of EGF signalling networks by the scaffold protein Shc1 miR-1279, miR-548j, miR-548m, and miR-548d-5p binding sites in CDSs of paralogous and orthologous PTPN12, MSH6, and ZEB1 Genes MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer.Regulation of the Src kinase-associated phosphoprotein 55 homologue by the protein tyrosine phosphatase PTP-PEST in the control of cell motility Protein tyrosine phosphatase UBASH3B is overexpressed in triple-negative breast cancer and promotes invasion and metastasis.Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma.Active kinase profiling, genetic and pharmacological data define mTOR as an important common target in triple-negative breast cancer.A New Bliss Independence Model to Analyze Drug Combination Data.BIMMER: a novel algorithm for detecting differential DNA methylation regions from MBDCap-seq data.PTP-PEST targets a novel tyrosine site in p120 catenin to control epithelial cell motility and Rho GTPase activity.Phospho-kinase profile of triple negative breast cancer and androgen receptor signaling.Identification and use of biomarkers in treatment strategies for triple-negative breast cancer subtypes.ER-alpha-cDNA as part of a bicistronic transcript gives rise to high frequency, long term, receptor expressing cell clones.Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.REST controls self-renewal and tumorigenic competence of human glioblastoma cells.Quantification of the host response proteome after mammalian reovirus T1L infection.A high-dimensional, deep-sequencing study of lung adenocarcinoma in female never-smokers A loss-of-function screen for phosphatases that regulate neurite outgrowth identifies PTPN12 as a negative regulator of TrkB tyrosine phosphorylation.Metformin and erlotinib synergize to inhibit basal breast cancer.Pharmacological profiling of kinase dependency in cell lines across triple-negative breast cancer subtypes.Adaptive responses to dasatinib-treated lung squamous cell cancer cells harboring DDR2 mutations.Triple-negative and basal-like breast cancer: implications for oncologists.Protein tyrosine phosphatase-PEST and β8 integrin regulate spatiotemporal patterns of RhoGDI1 activation in migrating cells An ShRNA Based Genetic Screen Identified Sesn2 as a Potential Tumor Suppressor in Lung Cancer via Suppression of Akt-mTOR-p70S6K Signaling ACAP4 protein cooperates with Grb2 protein to orchestrate epidermal growth factor-stimulated integrin β1 recycling in cell migration Elevated PI3K signaling drives multiple breast cancer subtypes.Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression.Tyrosine-protein phosphatase non-receptor type 12 expression is a good prognostic factor in resectable non-small cell lung cancer.The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1.Loss of brain-enriched miR-124 microRNA enhances stem-like traits and invasiveness of glioma cells A targeted RNAi screen of the breast cancer genome identifies KIF14 and TLN1 as genes that modulate docetaxel chemosensitivity in triple-negative breast cancer.The prognostic significance of tyrosine-protein phosphatase nonreceptor type 12 expression in nasopharyngeal carcinoma.Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer.Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility

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P2860

Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase

http://www.wikidata.org/entity/Q24294831

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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Activation of multiple proto-o ...... loss of the PTPN12 phosphatase

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C Kent Osborne

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Chad J Creighton

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Chunshui Zhou

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David A Wheeler

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Don X Nguyen

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Donna Muzny

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Earlene Schmitt

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Guang Hu

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Ilenia Migliaccio

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Jessica D Kessler

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P2860

Identification of protein tyrosine phosphatases associating with the PDGF receptor

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

The phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptor

Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition

Cloning and expression of PTP-PEST. A novel, human, nontransmembrane protein tyrosine phosphatase

MicroRNA-mediated switching of chromatin-remodelling complexes in neural development

Genome-wide association study identifies novel breast cancer susceptibility loci

A quantitative atlas of mitotic phosphorylation

Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.

SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation

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