ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation - Wikidata - wikimedia - TriplyDB

ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation

ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation

http://www.wikidata.org/entity/Q24523440

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Multiple ATR-Chk1 pathway proteins preferentially associate with checkpoint-inducing DNA substrates Human single-stranded DNA binding proteins are essential for maintaining genomic stability Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes E3 ligase RFWD3 participates in replication checkpoint control ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts BID binds to replication protein A and stimulates ATR function following replicative stress The replication fork: understanding the eukaryotic replication machinery and the challenges to genome duplication Human CtIP promotes DNA end resection DNA mismatch repair: molecular mechanism, cancer, and ageing Emerging common themes in regulation of PIKKs and PI3Ks Common mechanisms of PIKK regulation The Fanconi anemia protein FANCM is controlled by FANCD2 and the ATR/ATM pathways Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation Rapid activation of ATR by ionizing radiation requires ATM and Mre11 Discovery of Protein–Protein Interaction Inhibitors of Replication Protein A Surface Reengineering of RPA70N Enables Cocrystallization with an Inhibitor of the Replication Protein A Interaction Motif of ATR Interacting Protein Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function.Oligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardians Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome Identification and characterization of SMARCAL1 protein complexes Mutation of serine 1333 in the ATR HEAT repeats creates a hyperactive kinase ETAA1 acts at stalled replication forks to maintain genome integrity ATR: an essential regulator of genome integrity A dynamic model for replication protein A (RPA) function in DNA processing pathways The Dimeric Architecture of Checkpoint Kinases Mec1ATR and Tel1ATM Reveal a Common Structural Organization ATR checkpoint kinase and CRL1βTRCP collaborate to degrade ASF1a and thus repress genes overlapping with clusters of stalled replication forks.Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans.Telomere protection by TPP1/POT1 requires tethering to TIN2 SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathway Phosphorylation of Chk1 by ATM- and Rad3-related (ATR) in Xenopus egg extracts requires binding of ATRIP to ATR but not the stable DNA-binding or coiled-coil domains of ATRIP.Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences.ATRIP associates with replication protein A-coated ssDNA through multiple interactions.Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling.Herpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection.RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint.Function of a conserved checkpoint recruitment domain in ATRIP proteins.Function of the ATR N-terminal domain revealed by an ATM/ATR chimera.

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P2860

ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation

http://www.wikidata.org/entity/Q24523440

description

2005 nî lūn-bûn

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2005 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2005 թվականի մայիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

ATRIP binding to replication p ...... sable for Chk1 phosphorylation

@ast

ATRIP binding to replication p ...... sable for Chk1 phosphorylation

@en

ATRIP binding to replication p ...... sable for Chk1 phosphorylation

@en-gb

ATRIP binding to replication p ...... sable for Chk1 phosphorylation

@nl

type

label

ATRIP binding to replication p ...... sable for Chk1 phosphorylation

@ast

ATRIP binding to replication p ...... sable for Chk1 phosphorylation

@en

ATRIP binding to replication p ...... sable for Chk1 phosphorylation

@en-gb

ATRIP binding to replication p ...... sable for Chk1 phosphorylation

@nl

prefLabel

ATRIP binding to replication p ...... sable for Chk1 phosphorylation

@ast

ATRIP binding to replication p ...... sable for Chk1 phosphorylation

@en

ATRIP binding to replication p ...... sable for Chk1 phosphorylation

@en-gb

ATRIP binding to replication p ...... sable for Chk1 phosphorylation

@nl

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MBC.E04-11-1006

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Molecular Biology of the Cell

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ATRIP binding to replication p ...... sable for Chk1 phosphorylation

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P2093

David Cortez

http://www.w3.org/2001/XMLSchema#string

Heather L Ball

http://www.w3.org/2001/XMLSchema#string

Jeremy S Myers

http://www.w3.org/2001/XMLSchema#string

P2860

ATR kinase activity regulates the intranuclear translocation of ATR and RPA following ionizing radiation

Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling

Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

Replication protein A-mediated recruitment and activation of Rad17 complexes

Fission yeast Rad26 responds to DNA damage independently of Rad3

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast

Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo.

LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae

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2372-81

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scholarly article

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2016481

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10.1091/MBC.E04-11-1006

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5

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16

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15743907

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phosphorylation

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1087242

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