Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling
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Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpointInteractions of the human MCM-BP protein with MCM complex components and Dbf4Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylationReplication licensing and cancer--a fatal entanglement?Cdc7-Dbf4 and the human S checkpoint response to UVCThe Mcm2-7 replicative helicase: a promising chemotherapeutic targetSpy1 expression prevents normal cellular responses to DNA damage: inhibition of apoptosis and checkpoint activationProteomic identification of macrophage migration-inhibitory factor upon exposure to TiO2 particlesCdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architectureATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaksConserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damageDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMHepatitis B virus X protein induces apoptosis and cell cycle deregulation through interfering with DNA repair and checkpoint responses.Differential requirements for MCM proteins in DNA replication in Drosophila S2 cellsMcm4 C-terminal domain of MCM helicase prevents excessive formation of single-stranded DNA at stalled replication forksTipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress.Optimization based tumor classification from microarray gene expression data.The dynamics of E1A in regulating networks and canonical pathways in quiescent cellsDecreased MCM2-6 in Drosophila S2 cells does not generate significant DNA damage or cause a marked increase in sensitivity to replication interference.The interaction between checkpoint kinase 1 (Chk1) and the minichromosome maintenance (MCM) complex is required for DNA damage-induced Chk1 phosphorylation.Dimerization of the ATRIP protein through the coiled-coil motif and its implication to the maintenance of stalled replication forksMCM Paradox: Abundance of Eukaryotic Replicative Helicases and Genomic Integrity.Differential hRad17 expression by histologic subtype of ovarian cancer.Proteomic analysis of proton beam irradiated human melanoma cellsBRCA1 is required for postreplication repair after UV-induced DNA damagePhosphorylation of Minichromosome Maintenance 3 (MCM3) by Checkpoint Kinase 1 (Chk1) Negatively Regulates DNA Replication and Checkpoint Activation.Chromatin remodeler sucrose nonfermenting 2 homolog (SNF2H) is recruited onto DNA replication origins through interaction with Cdc10 protein-dependent transcript 1 (Cdt1) and promotes pre-replication complex formation.A comparative proteomic study identified LRPPRC and MCM7 as putative actors in imatinib mesylate cross-resistance in Lucena cell line.Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells.Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissueA genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint.The fission yeast minichromosome maintenance (MCM)-binding protein (MCM-BP), Mcb1, regulates MCM function during prereplicative complex formation in DNA replication.Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex.Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication.Reducing MCM levels in human primary T cells during the G(0)-->G(1) transition causes genomic instability during the first cell cyclePhosphorylation of minichromosome maintenance protein 7 (MCM7) by cyclin/cyclin-dependent kinase affects its function in cell cycle regulationDivergent S phase checkpoint activation arising from prereplicative complex deficiency controls cell survival.The Mcm complex: unwinding the mechanism of a replicative helicase.
P2860
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P248
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P2860
Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Interaction between human MCM7 ...... plication checkpoint signaling
@ast
Interaction between human MCM7 ...... plication checkpoint signaling
@en
Interaction between human MCM7 ...... plication checkpoint signaling
@en-gb
Interaction between human MCM7 ...... plication checkpoint signaling
@nl
type
label
Interaction between human MCM7 ...... plication checkpoint signaling
@ast
Interaction between human MCM7 ...... plication checkpoint signaling
@en
Interaction between human MCM7 ...... plication checkpoint signaling
@en-gb
Interaction between human MCM7 ...... plication checkpoint signaling
@nl
prefLabel
Interaction between human MCM7 ...... plication checkpoint signaling
@ast
Interaction between human MCM7 ...... plication checkpoint signaling
@en
Interaction between human MCM7 ...... plication checkpoint signaling
@en-gb
Interaction between human MCM7 ...... plication checkpoint signaling
@nl
P2093
P2860
P921
P356
P1433
P1476
Interaction between human MCM7 ...... plication checkpoint signaling
@en
P2093
Cheng-Chung Tsao
Christoph Geisen
Robert T Abraham
P2860
P304
P356
10.1038/SJ.EMBOJ.7600463
P407
P577
2004-11-24T00:00:00Z