Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family of the MEINOX TALE homeodomain transcription factors - Wikidata - wikimedia - TriplyDB

Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family of the MEINOX TALE homeodomain transcription factors

Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family of the MEINOX TALE homeodomain transcription factors

http://www.wikidata.org/entity/Q24528987

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Prep2: cloning and expression of a new prep family member Overexpression of PREP-1 in F9 teratocarcinoma cells leads to a functionally relevant increase of PBX-2 by preventing its degradation Involvement of Prep1 in the alphabeta T-cell receptor T-lymphocytic potential of hematopoietic precursors Subcellular localization of multiple PREP2 isoforms is regulated by actin, tubulin, and nuclear export Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype PBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter region Cooperative transcriptional activation by Klf4, Meis2, and Pbx1 TALE homeodomain proteins regulate site-specific terminal differentiation, LCE genes and epidermal barrier.Misexpression of Pknox2 in mouse limb bud mesenchyme perturbs zeugopod development and deltoid crest formation.Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow.Pbx homeodomain proteins: TALEnted regulators of limb patterning and outgrowth.Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates.MEIS1, PREP1, and PBX4 are differentially expressed in acute lymphoblastic leukemia: association of MEIS1 expression with higher proliferation and chemotherapy resistance.PBX1 nuclear export is regulated independently of PBX-MEINOX interaction by PKA phosphorylation of the PBC-B domain.The Interacting Domains of PREP1 and p160 are Endowed with a Remarkable Structural Stability.MEIS C termini harbor transcriptional activation domains that respond to cell signaling.Correlation Between Meis1 and Msi1 in Esophageal Squamous Cell Carcinoma.The role of Pbx1 in T cells.Prep1/Pbx2 complexes regulate CCL2 expression through the -2578 guanine polymorphism PKNOX2 is associated with formal thought disorder in schizophrenia: a meta-analysis of two genome-wide association studies.Cytogenetic and genetic evidence supports a role for the kainate-type glutamate receptor gene, GRIK4, in schizophrenia and bipolar disorder.

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P2860

Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family of the MEINOX TALE homeodomain transcription factors

http://www.wikidata.org/entity/Q24528987

description

2002 nî lūn-bûn

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2002年の論文

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Characterization of PREP2, a p ...... eodomain transcription factors

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Characterization of PREP2, a p ...... eodomain transcription factors

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Characterization of PREP2, a p ...... eodomain transcription factors

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Characterization of PREP2, a p ...... eodomain transcription factors

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C Fognani

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P2860

Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

Cloning of a novel homeobox-containing gene, PKNOX1, and mapping to human chromosome 21q22.3

Prep1, a novel functional partner of Pbx proteins.

The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity

Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals

PBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteins

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells

The subcellular localization of PBX1 and EXD proteins depends on nuclear import and export signals and is modulated by association with PREP1 and HTH

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