Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates.
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Role of HOXA9 in leukemia: dysregulation, cofactors and essential targetsPurification and characterization of a DNA-binding recombinant PREP1:PBX1 complexTwo decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia.The deficiency of tumor suppressor prep1 accelerates the onset of meis1- hoxa9 leukemogenesisPrep1 (pKnox1) regulates mouse embryonic HSC cycling and self-renewal affecting the Stat1-Sca1 IFN-dependent pathway.ChIP-Seq and RNA-Seq analyses identify components of the Wnt and Fgf signaling pathways as Prep1 target genes in mouse embryonic stem cells.Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow.Diversity of human and mouse homeobox gene expression in development and adult tissues.The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6.The splicing regulator PTBP1 controls the activity of the transcription factor Pbx1 during neuronal differentiation.The Widening Sphere of Influence of HOXB7 in Solid TumorsTo Be Specific or Not: The Critical Relationship Between Hox And TALE Proteins.Pbx1 is required for adult subventricular zone neurogenesis.Prep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis.PBX3 is a putative biomarker of aggressive prostate cancer.A hydrophobic residue in the TALE homeodomain of PBX1 promotes epithelial-to-mesenchymal transition of gastric carcinoma.Tumorigenesis by Meis1 overexpression is accompanied by a change of DNA target-sequence specificity which allows binding to the AP-1 elementHoxa2 selectively enhances Meis binding to change a branchial arch ground state.Targeting HOX/PBX dimers in cancer.The flexibility of a homeodomain transcription factor heterodimer and its allosteric regulation by DNA binding.The miR-17∼92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1The Interacting Domains of PREP1 and p160 are Endowed with a Remarkable Structural Stability.A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease.MEIS1 regulates early erythroid and megakaryocytic cell fate.Meis: New friends of Pax.A trans-Regulatory Code for the Forebrain Expression of Six3.2 in the Medaka Fish.Spleen hypoplasia leads to abnormal stress hematopoiesis in mice with loss of Pbx homeoproteins in splenic mesenchyme.De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects.Germ cell-intrinsic requirement for the homeodomain transcription factor PKnox1/Prep1 in adult spermatogenesis.Face morphogenesis is promoted by Pbx-dependent EMT via regulation of Snail1 during frontonasal prominence fusion.The PBX1 lupus susceptibility gene regulates CD44 expression.Arginine Methylation Regulates MEIS2 Nuclear Localization to Promote Neuronal Differentiation of Adult SVZ Progenitors.Distinct myocardial lineages break atrial symmetry during cardiogenesis in zebrafish.Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface.A direct interaction between two Restless Legs Syndrome predisposing genes: MEIS1 and SKOR1Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells
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Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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name
Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates.
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type
label
Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates.
@en
prefLabel
Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates.
@en
P2093
P2860
P921
P356
P1476
Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates.
@en
P2093
E Longobardi
Francesco Blasi
G De Florian
P2860
P356
10.1002/DVDY.24016
P577
2013-09-02T00:00:00Z
2014-01-01T00:00:00Z