Killing tumours by ceramide-induced apoptosis: a critique of available drugs
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Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermisA house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell deathThe expression of sphingosine kinase-1 in head and neck carcinomaα-TEA-induced death receptor dependent apoptosis involves activation of acid sphingomyelinase and elevated ceramide-enriched cell surface membranesCardiomyocyte aldose reductase causes heart failure and impairs recovery from ischemia.Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses.Proton NMR-based metabolite analyses of archived serial paired serum and urine samples from myeloma patients at different stages of disease activity identifies acetylcarnitine as a novel marker of active disease.Coupling in vitro and in vivo paradigm reveals a dose dependent inhibition of angiogenesis followed by initiation of autophagy by C6-ceramide.Cardiovascular effects of sphingosine-1-phosphate and other sphingomyelin metabolites.P-glycoprotein antagonists confer synergistic sensitivity to short-chain ceramide in human multidrug-resistant cancer cells.Preclinical Evaluation of Liposomal C8 Ceramide as a Potent anti-Hepatocellular Carcinoma Agent.Liposomal C6 Ceramide Activates Protein Phosphatase 1 to Inhibit Melanoma CellsTumor Necrosis Factor-α (TNFα)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death.Prolactin acts as a potent survival factor for human breast cancer cell lines.Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53.Expression of the follicular lymphoma variant translocation 1 gene in diffuse large B-cell lymphoma correlates with subtype and clinical outcome.Aberrant lipid metabolism: an emerging diagnostic and therapeutic target in ovarian cancer.Identification of C(6) -ceramide-interacting proteins in D6P2T Schwannoma cells.Signaling and regulatory functions of bioactive sphingolipids as therapeutic targets in multiple sclerosis.Allylic structures in cancer drugs and body metabolites that control cell life and death.Examining impacts of ceranib-2 on the proliferation, morphology and ultrastructure of human breast cancer cells.Involvement of de novo ceramide synthesis in gamma-tocopherol and gamma-tocotrienol-induced apoptosis in human breast cancer cells.Regulation of sphingosine-1-phosphate lyase gene expression by members of the GATA family of transcription factors.Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53.Stereoselective synthesis of (2S,3S,4Z)-4-fluoro-1,3-dihydroxy-2-(octadecanoylamino)octadec-4-ene, [(Z)-4-fluoroceramide], and its phase behavior at the air/water interface.Translational Aspects of Sphingolipid Metabolism in Renal Disorders.Ceramide species are elevated in human breast cancer and are associated with less aggressiveness.γ-Tocotrienol induces apoptosis in pancreatic cancer cells by upregulation of ceramide synthesis and modulation of sphingolipid transport.
P2860
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P2860
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@ast
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@en
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@en-gb
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@nl
type
label
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@ast
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@en
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@en-gb
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@nl
prefLabel
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@ast
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@en
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@en-gb
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@nl
P2860
P3181
P356
P1433
P1476
Killing tumours by ceramide-induced apoptosis: a critique of available drugs
@en
P2093
Norman S Radin
P2860
P304
P3181
P356
10.1042/BJ20021878
P407
P577
2003-04-15T00:00:00Z