Binding of cGMP to both allosteric sites of cGMP-binding cGMP-specific phosphodiesterase (PDE5) is required for its phosphorylation
about
Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)Isolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expressionStructure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptorMolecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11AConformation Changes, N-terminal Involvement, and cGMP Signal Relay in the Phosphodiesterase-5 GAF DomainERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regionsInteraction of guanylyl cyclase C with SH3 domain of Src tyrosine kinase. Yet another mechanism for desensitizationActivation of phosphodiesterase 5 and inhibition of guanylate cyclase by cGMP-dependent protein kinase in smooth musclePivotal effects of phosphodiesterase inhibitors on myocyte contractility and viability in normal and ischemic hearts.Differential expression of PDE5 in failing and nonfailing human myocardiumDirect activation of PDE5 by cGMP: long-term effects within NO/cGMP signalingPhosphodiesterase 11: a brief review of structure, expression and function.Hyperoxia increases phosphodiesterase 5 expression and activity in ovine fetal pulmonary artery smooth muscle cellsContractile agonists attenuate cGMP levels by stimulating phosphorylation of cGMP-specific PDE5; an effect mediated by RhoA/PKC-dependent inhibition of protein phosphatase 1Clinical and molecular genetics of the phosphodiesterases (PDEs).Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments.Novel alternative splice variants of cGMP-binding cGMP-specific phosphodiesterase.In vivo reconstitution of the negative feedback in nitric oxide/cGMP signaling: role of phosphodiesterase type 5 phosphorylation.Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.Ectopic expression of bovine type 5 phosphodiesterase confers a renal phenotype in Drosophila.Regulation of photoreceptor phosphodiesterase catalysis by its non-catalytic cGMP-binding sites.Phosphorylation of isolated human phosphodiesterase-5 regulatory domain induces an apparent conformational change and increases cGMP binding affinity.Phosphodiesterase type 5 and cancers: progress and challenges.3',5'-cIMP as Potential Second Messenger in the Vascular Wall.
P2860
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P2860
Binding of cGMP to both allosteric sites of cGMP-binding cGMP-specific phosphodiesterase (PDE5) is required for its phosphorylation
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Binding of cGMP to both allost ...... quired for its phosphorylation
@ast
Binding of cGMP to both allost ...... quired for its phosphorylation
@en
Binding of cGMP to both allost ...... quired for its phosphorylation
@en-gb
Binding of cGMP to both allost ...... quired for its phosphorylation
@nl
type
label
Binding of cGMP to both allost ...... quired for its phosphorylation
@ast
Binding of cGMP to both allost ...... quired for its phosphorylation
@en
Binding of cGMP to both allost ...... quired for its phosphorylation
@en-gb
Binding of cGMP to both allost ...... quired for its phosphorylation
@nl
prefLabel
Binding of cGMP to both allost ...... quired for its phosphorylation
@ast
Binding of cGMP to both allost ...... quired for its phosphorylation
@en
Binding of cGMP to both allost ...... quired for its phosphorylation
@en-gb
Binding of cGMP to both allost ...... quired for its phosphorylation
@nl
P2093
P2860
P356
P1433
P1476
Binding of cGMP to both allost ...... quired for its phosphorylation
@en
P2093
J D Corbin
S H Francis
P2860
P304
P356
10.1042/BJ3290505
P407
P478
329 ( Pt 3)
P577
1998-02-01T00:00:00Z