Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation.
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Receptor-mediated stimulation of lipid signalling pathways in CHO cells elicits the rapid transient induction of the PDE1B isoform of Ca2+/calmodulin-stimulated cAMP phosphodiesteraseBinding of cGMP to both allosteric sites of cGMP-binding cGMP-specific phosphodiesterase (PDE5) is required for its phosphorylationStructure, localization, and regulation of cGMP-inhibited phosphodiesterase (PDE3)Increased lipolysis and energy expenditure in a mouse model with severely impaired glucagon secretionInsulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase AktImportant role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta-cell exocytosis and release of insulinAdrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytesMolecular cloning and expression of human myocardial cGMP-inhibited cAMP phosphodiesterase.Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets.Insulin activates a 70-kDa S6 kinase through serine/threonine-specific phosphorylation of the enzyme polypeptide.A combination of exercise and capsinoid supplementation additively suppresses diet-induced obesity by increasing energy expenditure in mice.Insulin attenuates agonist-mediated calcium mobilization in cultured rat vascular smooth muscle cells.Sarcoplasmic reticulum-associated cyclic adenosine 5'-monophosphate phosphodiesterase activity in normal and failing human hearts.Brain insulin controls adipose tissue lipolysis and lipogenesis.PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalizationYin and Yang of hypothalamic insulin and leptin signaling in regulating white adipose tissue metabolismThe Role of PDE3B Phosphorylation in the Inhibition of Lipolysis by Insulin.Phosphodiesterase-5A and neutral endopeptidase activities in human adipocytes do not control atrial natriuretic peptide-mediated lipolysis.Tumor necrosis factor and CD11/CD18 (beta 2) integrins act synergistically to lower cAMP in human neutrophils.Insulin signalling in human adipose tissue.Multiple transcripts for the human cardiac form of the cGMP-inhibited cAMP phosphodiesterase.Glucose uptake and lipid metabolism are impaired in epicardial adipose tissue from heart failure patients with or without diabetes.The effects of pentoxifylline adminstration on fracture healing in a postmenopausal osteoporotic rat model.Sphingosine-1-phosphate rapidly increases cortisol biosynthesis and the expression of genes involved in cholesterol uptake and transport in H295R adrenocortical cellsCellular aspects of fuel mobilization and selection in white adipocytes.Activation of the cAMP-specific phosphodiesterase PDE4D3 by phosphorylation. Identification and function of an inhibitory domain.Adipocyte hormone-sensitive lipase: a major regulator of lipid metabolism.Obesity induces pro-inflammatory B cells and impairs B cell function in old mice.Regulation of adiponectin and leptin secretion and expression by insulin through a PI3K-PDE3B dependent mechanism in rat primary adipocytes.Phosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: deactivation of PDE3B in vitro by protein phosphatase type 2A.Down-regulation of cyclic-nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumour necrosis factor alpha and cAMPActivity of cyclic AMP phosphodiesterases and adenylyl cyclase in peripheral nerve after crush and permanent transection injuries.mRNA expression and antilipolytic role of phosphodiesterase 4 in rat adipocytes in vitro.Widdrol-induced lipolysis is mediated by PKC and MEK/ERK in 3T3-L1 adipocytes.Fat accumulation in the rat during early pregnancy is modulated by enhanced insulin responsiveness.Protein kinase B/Akt induces resumption of meiosis in Xenopus oocytes.Syndrome of lipoatrophic diabetes, vitamin D resistant rickets, and persistent Müllerian ducts in a Turkish boy born to consanguineous parents.
P2860
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P2860
Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Evidence that insulin and isop ...... fat cells by phosphorylation.
@en
Evidence that insulin and isop ...... fat cells by phosphorylation.
@nl
type
label
Evidence that insulin and isop ...... fat cells by phosphorylation.
@en
Evidence that insulin and isop ...... fat cells by phosphorylation.
@nl
prefLabel
Evidence that insulin and isop ...... fat cells by phosphorylation.
@en
Evidence that insulin and isop ...... fat cells by phosphorylation.
@nl
P2093
P2860
P356
P1476
Evidence that insulin and isop ...... fat cells by phosphorylation.
@en
P2093
Belfrage P
Degerman E
Manganiello VC
Tornqvist H
P2860
P304
P356
10.1073/PNAS.87.2.533
P407
P577
1990-01-01T00:00:00Z