Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo - Wikidata - wikimedia - TriplyDB

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

http://www.wikidata.org/entity/Q24531714

about

Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesions c-Src regulates Akt signaling in response to ghrelin via beta-arrestin signaling-independent and -dependent mechanisms Regulation of TNF-induced oxygen radical production in human neutrophils: role of delta-PKC 3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling The PI3K-PDK1 connection: more than just a road to PKB The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cells A comprehensive pathway map of epidermal growth factor receptor signaling AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation.Wortmannin reduces insulin signaling and death in seizure-prone Pcmt1-/- mice PPARδ activation acts cooperatively with 3-phosphoinositide-dependent protein kinase-1 to enhance mammary tumorigenesis High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site.Phosphorylation of the regulatory subunit of smooth muscle protein phosphatase 1M at Thr850 induces its dissociation from myosin Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3 Phosphatidylinositol 3-kinase activation is required for stress protocol-induced modification of hippocampal synaptic plasticity Regulation of transforming growth factor-beta signaling and PDK1 kinase activity by physical interaction between PDK1 and serine-threonine kinase receptor-associated protein Interaction of phospholipase D1 with a casein-kinase-2-like serine kinase Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton Identification of direct target engagement biomarkers for kinase-targeted therapeutics Ubiquitin-specific protease 4 inhibits mono-ubiquitination of the master growth factor signaling kinase PDK1 Essential role of PDK1 in regulating endothelial cell migration Regulation of PTEN stability and activity by Plk3 Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit 9-Aminoacridine inhibition of HIV-1 Tat dependent transcription.Sex differences in the activity of signalling pathways and expression of G-protein-coupled receptor kinases in the neonatal ventral hippocampal lesion model of schizophrenia.Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1.PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle.Strigolactones: a novel class of phytohormones that inhibit the growth and survival of breast cancer cells and breast cancer stem-like enriched mammosphere cells.Aging-associated dysfunction of Akt/protein kinase B: S-nitrosylation and acetaminophen intervention.Reciprocal negative regulation of PDK1 and ASK1 signaling by direct interaction and phosphorylation.Inositol hexaphosphate suppresses growth and induces apoptosis in prostate carcinoma cells in culture and nude mouse xenograft: PI3K-Akt pathway as potential target.A small molecule inhibits Akt through direct binding to Akt and preventing Akt membrane translocation.Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation.Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor.Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways The molecular mechanism of leptin secretion and expression induced by aristolochic acid in kidney fibroblast Membrane Trafficking of Collecting Duct Water Channel Protein AQP2 Regulated by Akt/AS160.

P2860

Q24298708-03920902-D416-4FC8-8113-7F25F37477BB Q24317611-6332FEAF-13E8-4D5C-BE98-9F23977A1672 Q24321292-ABD8F0A7-F503-413D-A272-1890E4876A96 Q24337691-ED6C7541-7F81-48F0-90E8-5E059E4B9BE7 Q24531972-4E8282A7-FA23-466B-B204-1FF109D662DD Q24551026-DDBA0ED4-2769-4BC7-B828-78E2DBC819B2 Q24672490-7BA526C1-B6D1-4699-975B-499081AF80F0 Q27309773-2B623C0B-4004-49B4-9D03-68230566423B Q27315945-216394C0-DBA5-4F83-A13C-FA222E028A91 Q27437643-4BBB37BA-DF75-42B6-9335-966841212D54 Q27639475-89751CF5-8DC4-4113-8044-9021A0169376 Q28200871-7C93F625-734A-4EB9-B288-917BCAA90C16 Q28217875-A2183AA7-982E-4BE9-9231-12DF565FFF4A Q28259863-800D3B8F-6017-4119-8D64-EA9C658DEBD7 Q28279119-EA81106A-8717-434D-AE71-EED70DDE1A2E Q28348365-DD67F057-D2A6-4563-9D70-6EC858FD8F1A Q28389726-FFDD3C26-3566-485F-A86B-67FAC535E276 Q28475032-7C660AB9-9E9F-44DA-A02A-2F91E79E04BC Q28477593-9002FFD4-F459-4416-A736-AA95441A54FA Q28480531-79B3E342-D04E-4D16-9A76-958C706C23E0 Q28509286-85B783B0-C7E7-4ECC-A7E5-7DC8E719B23E Q28512686-646390DB-31E0-47F6-8505-C3F83514FDE8 Q28564173-244ADA78-D5CE-4593-941F-7E3BD2E50A2C Q28587753-3F7EBD21-4226-4F39-8A85-4FEA9A4D43E3 Q28646131-9D9E3C17-75FC-4D20-AFB9-CC6C5B4F7062 Q30008900-E52FFA9B-E574-48A0-822F-D8ACCDC26265 Q30438975-09AA5743-7D7F-475D-B936-BF3D66233645 Q30470945-9F7E48A2-FEA1-4116-969C-496EF38F717D Q31626065-A721E54F-CE17-4078-B453-2FC0A8037AB0 Q33341346-FDE0850E-8888-4A24-9D6C-51E90FF44DD9 Q33353296-D4B21C4A-E70C-4E3D-B98A-784DA9F67C36 Q33488518-73DCBCC6-4112-4E19-AC6B-610C904ACAB0 Q33593885-E8D2556B-251A-42C1-B0F7-E0FFB56EE5B1 Q33644080-1045D045-8226-49CC-AB1E-D8C9BE4578D9 Q33707181-068AED35-1FA5-4E0B-AD5E-EB687B6C15FC Q33707626-EC5FFE90-7499-4950-9181-FC874C43A1F6 Q33722849-18AD836E-BEFC-47A0-9616-5B3BA8506AC7 Q33737298-BA6C7206-4D62-4D4B-AC2E-5141E15B2C31 Q33815433-19D223BB-6C47-45C1-9A13-5A0BDFFABEB5 Q33863522-C08D1250-CFD6-4600-A0AF-D0970CEE1781

P2860

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

http://www.wikidata.org/entity/Q24531714

description

1999 nî lūn-bûn

@nan

1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@ast

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@en

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@en-gb

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@nl

type

label

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@ast

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@en

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@en-gb

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@nl

prefLabel

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@ast

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@en

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@en-gb

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@nl

P1433

Q24531714-7B25CDF9-A7E2-4338-95BC-1015B1BED683

P1476

Q24531714-D5A044C3-EDEB-44FC-9245-1C92557CE5A7

P2093

Q24531714-816FC440-04A3-439D-AAAE-D2633DE42EC8

Q24531714-A25A06C4-5F29-4C64-9EBA-2CBD438A49EA

P2860

Q24531714-0B69A5DF-BAAB-4523-9E85-ABEC1EFA84FB

Q24531714-0C15BF5B-A9BC-47DD-A415-6FF93B522C00

Q24531714-1D05ACBB-7537-47B2-95E9-ABD447FFE9C0

Q24531714-2F0BAC75-9E80-4A8E-AE9C-42534F4B2BD3

Q24531714-36E495E4-4A47-4B35-99AE-AA68A629A05D

Q24531714-3DFCE35E-7401-43D0-AD79-236A634EF3D6

Q24531714-42C1436A-FDB5-4A3E-8A5F-7BDAC342A761

Q24531714-59B9031D-3EF9-4B42-8BA6-AC1A4C910A55

Q24531714-7C5E542C-1E7F-4540-81F6-0655B592790F

Q24531714-820171DC-6551-4512-9B17-B53CC182CD72

P304

Q24531714-5FEBC295-1CD6-44D4-92D9-49233ABE4707

P31

Q24531714-C2D8F783-144F-4C45-89BA-9124A418EDBC

P3181

Q24531714-0913BB8E-06B4-4F27-9B66-E588B6E0BE3F

P356

Q24531714-09ECC070-D39C-4E47-8CD8-2641503E2C1B

Q24531714-37F555CB-81DF-47B3-BA5C-DDE44596F3B2

P407

Q24531714-D4E63F90-E038-4CBB-ACB6-094C369FE63C

P478

Q24531714-68A4B5B0-16A7-4809-A320-4A8F9C057652

P50

Q24531714-BE4D2401-6887-4C6A-BB7D-B58F6F14D9F2

P577

Q24531714-4C27C73A-D396-467D-A475-DD86A055695F

P5875

Q24531714-CCF7CF27-3121-41E5-BBDA-D2C1D5E83E07

P698

Q24531714-1C971A04-6467-4305-BE6F-AF17A2494150

P921

Q24531714-D5707023-934A-4E1E-899C-351E04CD40F2

P932

Q24531714-E778D74B-F64D-49C3-9766-E61A87FC8015

P3181

P356

0264-6021:3420287

P1433

Biochemical Journal

P1476

Phosphorylation of Ser-241 is ...... tes of phosphorylation in vivo

@en

P2093

D R Alessi

http://www.w3.org/2001/XMLSchema#string

N A Morrice

http://www.w3.org/2001/XMLSchema#string

P2860

Mechanism of activation of protein kinase B by insulin and IGF-1

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

The extended protein kinase C superfamily

Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans

Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast.

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

Intracellular signalling: PDK1--a kinase at the hub of things.

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase.

P304

287-92

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

4778461

http://www.w3.org/2001/XMLSchema#string

P356

10.1042/0264-6021:3420287

http://www.w3.org/2001/XMLSchema#string

10.1042/BJ3420287

http://www.w3.org/2001/XMLSchema#string

P407

P478

342 ( Pt 2)

http://www.w3.org/2001/XMLSchema#string

P50

Antonio Casamayor

P577

1999-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

240227472

http://www.w3.org/2001/XMLSchema#string

P698

10455013

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

1220463

http://www.w3.org/2001/XMLSchema#string