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A comprehensive pathway map of epidermal growth factor receptor signaling

A comprehensive pathway map of epidermal growth factor receptor signaling

http://www.wikidata.org/entity/Q24672490

about

The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid Genome-wide review of transcriptional complexity in mouse protein kinases and phosphatases.Cell signaling by receptor tyrosine kinases Markers of resistance to anti-EGFR therapy in colorectal cancer A comprehensive manually curated reaction map of RANKL/RANK-signaling pathway Network, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system New advances in targeted gastric cancer treatment Current and emerging therapies in unresectable and recurrent gastric cancer MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer Integration of 'omics' data in aging research: from biomarkers to systems biology Introductory review of computational cell cycle modeling Molecular recognition of gangliosides and their potential for cancer immunotherapies Multiscale models of cell signaling.Cortical high-density counterstream architectures Gastric Cancer: New Drugs - New Strategies Asymmetric migration of human keratinocytes under mechanical stretch and cocultured fibroblasts in a wound repair model Inhibition of Receptor Dimerization as a Novel Negative Feedback Mechanism of EGFR Signaling A MAPK-Driven Feedback Loop Suppresses Rac Activity to Promote RhoA-Driven Cancer Cell Invasion Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states.Modelling the Structure and Dynamics of Biological Pathways A bow-tie genetic architecture for morphogenesis suggested by a genome-wide RNAi screen in Caenorhabditis elegans Epidermal growth factor is a potential biomarker for poor cetuximab response in tongue cancer cells.Analyzing and interpreting genome data at the network level with ConsensusPathDB The 3rd DBCLS BioHackathon: improving life science data integration with Semantic Web technologies Mechanisms of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance and Strategies to Overcome Resistance in Lung Adenocarcinoma Modelling GTPase dynamics to understand RhoA-driven cancer cell invasion Epidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancer Modeling HER2 effects on cell behavior from mass spectrometry phosphotyrosine data Stimulus design for model selection and validation in cell signaling Identification of potent EGFR inhibitors from TCM Database@Taiwan Identification of biochemical network modules based on shortest retroactive distances Modeling of tumor progression in NSCLC and intrinsic resistance to TKI in loss of PTEN expression Magnetic nanoparticles as mediators of ligand-free activation of EGFR signaling Integrative modelling of the influence of MAPK network on cancer cell fate decision Combining machine learning systems and multiple docking simulation packages to improve docking prediction reliability for network pharmacology Quantitative characterization of cellular membrane-receptor heterogeneity through statistical and computational modeling Synergistic interaction between selective drugs in cell populations models Comprehensive Map of Molecules Implicated in Obesity Bridging Mechanistic and Phenomenological Models of Complex Biological Systems Toward an integrated software platform for systems pharmacology

P2860

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P2860

A comprehensive pathway map of epidermal growth factor receptor signaling

http://www.wikidata.org/entity/Q24672490

description

2005 nî lūn-bûn

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2005年の論文

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2005年論文

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name

A comprehensive pathway map of epidermal growth factor receptor signaling

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A comprehensive pathway map of epidermal growth factor receptor signaling

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A comprehensive pathway map of epidermal growth factor receptor signaling

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type

label

A comprehensive pathway map of epidermal growth factor receptor signaling

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A comprehensive pathway map of epidermal growth factor receptor signaling

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A comprehensive pathway map of epidermal growth factor receptor signaling

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prefLabel

A comprehensive pathway map of epidermal growth factor receptor signaling

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A comprehensive pathway map of epidermal growth factor receptor signaling

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A comprehensive pathway map of epidermal growth factor receptor signaling

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Molecular Systems Biology

P1476

A comprehensive pathway map of epidermal growth factor receptor signaling

@en

P2093

Akira Funahashi

http://www.w3.org/2001/XMLSchema#string

Hiroaki Kitano

http://www.w3.org/2001/XMLSchema#string

Kanae Oda

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Yukiko Matsuoka

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P2860

Characterization of a naturally occurring ErbB4 isoform that does not bind or activate phosphatidyl inositol 3-kinase

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

Tyrosines 1148 and 1173 of activated human epidermal growth factor receptors are binding sites of Shc in intact cells

Bcr encodes a GTPase-activating protein for p21rac

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

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2005.0010

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233303

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10.1038/MSB4100014

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1

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1

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7053713

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16729045

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information system

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1681468

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