Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155
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p21-Activated kinase 1 (Pak1) phosphorylates BAD directly at serine 111 in vitro and indirectly through Raf-1 at serine 112Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XLProtection from rapamycin-induced apoptosis by insulin-like growth factor-I is partially dependent on protein kinase C signalingERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xLProtein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosisWNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrateRegulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblastsInvolvement of 14-3-3 Proteins in Regulating Tumor Progression of Hepatocellular CarcinomaLipoarabinomannan from Mycobacterium tuberculosis promotes macrophage survival by phosphorylating Bad through a phosphatidylinositol 3-kinase/Akt pathwayPhosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowthBinding of activated alpha2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMKSurvival-factor-induced phosphorylation of Bad results in its dissociation from Bcl-x(L) but not Bcl-2Serine 58 of 14-3-3zeta is a molecular switch regulating ASK1 and oxidant stress-induced cell deathIdentification of a novel phosphorylation site, Ser-170, as a regulator of bad pro-apoptotic activityContrasting roles of neuronal Msk1 and Rsk2 in Bad phosphorylation and feedback regulation of Erk signallingP2Y receptors activate neuroprotective mechanisms in astrocytic cellsPhosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's diseasep70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BADCCProf: exploring conformational change profile of proteins.Phosphodiesterase type 4 inhibitor rolipram improves survival of spiral ganglion neurons in vitroKinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids.Inhibition of calcium/calmodulin-dependent protein kinase kinase by protein 14-3-3.Persistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus.p90 ribosomal S6 kinase 1 (RSK1) and the catalytic subunit of protein kinase A (PKA) compete for binding the pseudosubstrate region of PKAR1alpha: role in the regulation of PKA and RSK1 activities.Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of RAS activation.Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation.Dynamics of the G protein-coupled vasopressin V2 receptor signaling network revealed by quantitative phosphoproteomics.Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties.mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD).14-3-3 proteins: key regulators of cell division, signalling and apoptosis.PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling.Subcellular localization and biological actions of activated RSK1 are determined by its interactions with subunits of cyclic AMP-dependent protein kinase.BAD-mediated apoptotic pathway is associated with human cancer developmentInhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2BAD phosphorylation determines ovarian cancer chemosensitivity and patient survival.Mitochondrial dysfunction in T cells of patients with systemic lupus erythematosus.Proteolytic regulation of the mitochondrial cAMP-dependent protein kinase.Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and AktCyclooxygenase-2 knockdown using retinoic acid chalcone (RAC), a promising therapeutic strategy for colon cancer
P2860
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P2860
Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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name
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@ast
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@en
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@en-gb
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@nl
type
label
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@ast
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@en
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@en-gb
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@nl
prefLabel
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@ast
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@en
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@en-gb
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@nl
P2093
P2860
P3181
P1433
P1476
Regulation of BAD by cAMP-depe ...... lation of a novel site, Ser155
@en
P2093
J M Lizcano
Jose M. LIZCANO
Nick MORRICE
Philip COHEN
P2860
P3181
P356
10.1042/0264-6021:3490547
10.1042/BJ3490547
P407
P577
2000-07-15T00:00:00Z