Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis
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Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XLYap1 acts downstream of α-catenin to control epidermal proliferationNeutrophil apoptosis mediated by nicotinic acid receptors (GPR109A)Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction14-3-3zeta mediates resistance of diffuse large B cell lymphoma to an anthracycline-based chemotherapeutic regimenModulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acidsLB100, a small molecule inhibitor of PP2A with potent chemo- and radio-sensitizing potential14-3-3 zeta as novel molecular target for cancer therapyThe spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fissionIntrinsically disordered proteins in bcl-2 regulated apoptosis.PP2A regulates the pro-apoptotic activity of FOXO1.Interdependence of Bad and Puma during ionizing-radiation-induced apoptosis.BAD detects coincidence of G2/M phase and growth factor deprivation to regulate apoptosis.Deletion of the cruciform binding domain in CBP/14-3-3 displays reduced origin binding and initiation of DNA replication in budding yeast.Over-expression of 14-3-3zeta is an early event in oral cancer.Chronic NMDA administration to rats increases brain pro-apoptotic factors while decreasing anti-Apoptotic factors and causes cell death.Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT.In vivo discovery of immunotherapy targets in the tumour microenvironment.14-3-3 zeta is a molecular target in guggulsterone induced apoptosis in head and neck cancer cells.Pim-1 kinase protects mitochondrial integrity in cardiomyocytes.Unfertilized Xenopus eggs die by Bad-dependent apoptosis under the control of Cdk1 and JNK.Inhibition of protein phosphatase 2A (PP2A) prevents Mcl-1 protein dephosphorylation at the Thr-163/Ser-159 phosphodegron, dramatically reducing expression in Mcl-1-amplified lymphoma cells.Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.Phenylarsine oxide binding reveals redox-active and potential regulatory vicinal thiols on the catalytic subunit of protein phosphatase 2A.A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins.Mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of spinocerebellar ataxia type 12 (SCA12)Induction of PP2A Bβ, a regulator of IL-2 deprivation-induced T-cell apoptosis, is deficient in systemic lupus erythematosus.SET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin lymphoma: a predictor of aggressive disease and a new treatment target.Targeting the actin cytoskeleton: selective antitumor action via trapping PKCɛuPAR and cathepsin B downregulation induces apoptosis by targeting calcineurin A to BAD via Bcl-2 in gliomaMouse model for probing tumor suppressor activity of protein phosphatase 2A in diverse signaling pathways.Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 PhosphorylationInvolvement of ceramide in cell death responses in the pulmonary circulation.Downregulation of ANP32B exerts anti-apoptotic effects in hepatocellular carcinomaThe Pim kinases control rapamycin-resistant T cell survival and activation.The B56γ3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1.Phosphorylation-dependent interaction with 14-3-3 in the regulation of bad trafficking in retinal ganglion cells.Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis.Identification of replication-competent HSV-1 Cgal+ strain signaling targets in human hepatoma cells by functional organelle proteomics.Autophagy postpones apoptotic cell death in PRRSV infection through Bad-Beclin1 interaction.
P2860
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P248
Q21284163-2004CB55-95D8-44B8-AC72-8C5497A80274Q24294904-4F571030-3DB3-450F-91B0-2C8C8E41C2CEQ24297428-C4122C49-7DBF-43DF-84D5-99BCF28909ECQ24602385-7C50CA3C-2203-4D42-A996-D12EB5B3D7F5Q24658236-72A270A9-6DC5-4488-B8B5-DB63B0434E48Q24674656-5696981F-AA5B-459F-B98E-430E07E3FCACQ26865711-89D77A9D-C14C-46E8-B100-73F757693B0EQ28264735-DFD73C7A-29EA-4DC7-BC68-BD495C3D01CBQ28581352-EEB92E2A-5266-444A-814E-7B8FE346D169Q30389323-2BCC1CF8-470A-4659-97A5-BD4F56D2BE02Q30440004-6C8D57C3-D87C-419F-95A6-8B29604CBB7AQ31151393-0A424418-9EFB-44FE-8659-517C7E2EF4FCQ33215310-9CEABAB9-6942-40BC-A4D5-0B6AE0EE331AQ33281965-39EDE902-4510-4322-B1CF-B3683E948AA1Q33296339-05EC97F5-3D34-4DD4-AC94-F1545F808D8CQ33507174-5F92790E-0CEC-4D44-B68C-665FD222243EQ33721192-FEC236C0-6DFF-4044-B230-1616290E8A15Q33736396-F983434C-43E7-4619-85F5-C27DEF09CFBFQ33758993-F2C92414-A313-454C-9C6C-33AFE314B829Q33828487-DE09AFC7-72B2-4E04-B642-662ACED8DC6CQ33999964-E88E10DF-DA01-4574-AC5D-B4935E06F0ADQ34070349-DAB5532A-5BF1-4879-884E-61FA40D6029CQ34125987-203EBDAA-750B-4A6C-AD4D-14BB14F73E42Q34600549-3D78AFE1-3F02-499C-B7A1-5CBB71E7E75AQ34609728-2CBAF4B2-73D9-4042-B4A9-A01A0AFDABFBQ35065260-B573FEC3-5589-4479-8253-4725BEA74B6BQ35134056-4F065799-A5A4-47B5-B471-8D1BD0F42880Q35483640-4B167182-5D33-451C-B299-967CD5D95A6FQ35679589-36A27FE8-E65A-43D6-B61B-ED5F55C20A92Q35776472-F257C1DB-668D-4D5A-88BC-80C3D4F7E055Q35859963-892E21EC-D222-4E29-BF23-3176954864CAQ35860938-AC9D82D6-F63B-4364-B295-C6867A4652B0Q35983863-62727452-37C8-4E83-9063-C8CF991E8A80Q36367144-C5E33BF0-9B24-481B-B087-3659C03C5040Q36402605-3284F514-3E1D-43F4-A950-E83E95405370Q36782507-27BC7DEA-7FA8-4763-838B-089DBA3993C1Q36808374-1B89DD03-A239-436C-8A3C-3DD530105BE5Q37071327-D4D52E24-0B05-4062-A8CE-A5763EBB863BQ37154463-B3213117-8DA9-4854-B2FF-DED0142C4B32Q37197322-0FFC3B7E-DD22-4E58-B2C4-FCB277598DD6
P2860
Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@ast
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@en
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@en-gb
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@nl
type
label
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@ast
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@en
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@en-gb
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@nl
prefLabel
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@ast
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@en
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@en-gb
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@nl
P2093
P2860
P921
P1476
Protein phosphatase 2A dephosp ...... ole for BAD-mediated apoptosis
@en
P2093
Chi-Wu Chiang
Christina Parkhurst
Cindy Kanies
Elizabeth Yang
Kwang Woon Kim
Minhui Xie
Travis Henry
Wei Bin Fang
P2860
P304
P356
10.1128/MCB.23.18.6350-6362.2003
P407
P577
2003-09-01T00:00:00Z