Basis for prokaryotic specificity of action of aminoglycoside antibiotics. - Wikidata - wikimedia - TriplyDB

Basis for prokaryotic specificity of action of aminoglycoside antibiotics.

Basis for prokaryotic specificity of action of aminoglycoside antibiotics.

http://www.wikidata.org/entity/Q24534157

about

Two conformational states in the crystal structure of the Homo sapiens cytoplasmic ribosomal decoding A site.Antibiotics that target protein synthesis Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics.A Steric Block in Translation Caused by the Antibiotic Spectinomycin Allosteric control of the ribosome by small-molecule antibiotics.A structural basis for the antibiotic resistance conferred by an A1408G mutation in 16S rRNA and for the antiprotozoal activity of aminoglycosides The Impact of Aminoglycosides on the Dynamics of Translation Elongation Selectivity of stop codon recognition in translation termination is modulated by multiple conformations of GTS loop in eRF1 4′-O-substitutions determine selectivity of aminoglycoside antibiotics The ribosome-bound chaperones RAC and Ssb1/2p are required for accurate translation in Saccharomyces cerevisiae.Aminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistance Determination of therapeutic equivalence of generic products of gentamicin in the neutropenic mouse thigh infection model A novel role of cytosolic protein synthesis inhibition in aminoglycoside ototoxicity.Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity.Aminoglycoside activity observed on single pre-translocation ribosome complexes.Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes The unfolded protein response affects readthrough of premature termination codons Correction of genetic disease by making sense from nonsense.A mutation in the decoding center of Thermus thermophilus 16S rRNA suggests a novel mechanism of streptomycin resistance.Molecular characterization of amikacin, kanamycin and capreomycin resistance in M/XDR-TB strains isolated in Thailand.Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic.Evidence of efficient stop codon readthrough in four mammalian genes A comprehensive analysis of translational missense errors in the yeast Saccharomyces cerevisiae.Comparison of the next-generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacin.Identification and evaluation of improved 4'-O-(alkyl) 4,5-disubstituted 2-deoxystreptamines as next-generation aminoglycoside antibiotics.Mutations conferring aminoglycoside and spectinomycin resistance in Borrelia burgdorferi.Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system Antibiotic selectivity for prokaryotic vs. eukaryotic decoding sites.Genomic analysis reveals distinct concentration-dependent evolutionary trajectories for antibiotic resistance in Escherichia coli.Role of 16S rRNA Helix 44 in Ribosomal Resistance to Hygromycin B Plasmid-mediated high-level resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation Suppression of nonsense mutations as a therapeutic approach to treat genetic diseases.RNA-seq analysis of the effect of kanamycin and the ABC transporter AtWBC19 on Arabidopsis thaliana seedlings reveals changes in metal content.Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions Activation of the dormant secondary metabolite production by introducing gentamicin-resistance in a marine-derived Penicillium purpurogenum G59 2-Deoxystreptamine Conjugates by Truncation-Derivatization of Neomycin Engineering the rRNA decoding site of eukaryotic cytosolic ribosomes in bacteria Suppression of premature termination codons as a therapeutic approach.Direct observation of aminoglycoside-RNA binding by localized surface plasmon resonance spectroscopy.Designer aminoglycosides: the race to develop improved antibiotics and compounds for the treatment of human genetic diseases.

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P2860

Basis for prokaryotic specificity of action of aminoglycoside antibiotics.

http://www.wikidata.org/entity/Q24534157

description

1999 nî lūn-bûn

@nan

1999 թուականի Յունիսին հրատարակուած գիտական յօդուած

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1999 թվականի հունիսին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Basis for prokaryotic specificity of action of aminoglycoside antibiotics

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Basis for prokaryotic specificity of action of aminoglycoside antibiotics.

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Basis for prokaryotic specificity of action of aminoglycoside antibiotics.

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Basis for prokaryotic specificity of action of aminoglycoside antibiotics

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Basis for prokaryotic specificity of action of aminoglycoside antibiotics.

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Basis for prokaryotic specificity of action of aminoglycoside antibiotics.

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Basis for prokaryotic specificity of action of aminoglycoside antibiotics

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Basis for prokaryotic specificity of action of aminoglycoside antibiotics.

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Basis for prokaryotic specificity of action of aminoglycoside antibiotics.

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The EMBO Journal

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Basis for prokaryotic specificity of action of aminoglycoside antibiotics.

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J D Puglisi

http://www.w3.org/2001/XMLSchema#string

M I Recht

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P2860

Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic

Mechanism of resistance to amikacin and kanamycin in Mycobacterium tuberculosis.

Interaction of antibiotics with functional sites in 16S ribosomal RNA

Structural origins of gentamicin antibiotic action

Susceptibility of Giardia lamblia to aminoglycoside protein synthesis inhibitors: correlation with rRNA structure.

Interaction of antibiotics with A- and P-site-specific bases in 16S ribosomal RNA

Effect of mutations in the A site of 16 S rRNA on aminoglycoside antibiotic-ribosome interaction.

RNA sequence determinants for aminoglycoside binding to an A-site rRNA model oligonucleotide.

Mistranslation in a eucaryotic organism.

Mistranslation in E. coli.

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scholarly article

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2943640

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10.1093/EMBOJ/18.11.3133

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11

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Stephen Douthwaite

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