A Steric Block in Translation Caused by the Antibiotic Spectinomycin - Wikidata - wikimedia - TriplyDB

A Steric Block in Translation Caused by the Antibiotic Spectinomycin

A Steric Block in Translation Caused by the Antibiotic Spectinomycin

http://www.wikidata.org/entity/Q27647153

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Structural insights into ribosome translocation New agents for the treatment of drug-resistant Mycobacterium tuberculosis Antibiotics that target protein synthesis Antiviral activity of geneticin against dengue virus.Structural basis for hygromycin B inhibition of protein biosynthesis Structures of the ribosome in intermediate states of ratcheting Crystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1 A dynamic structural model of expanded RNA CAG repeats: a refined X-ray structure and computational investigations using molecular dynamics and umbrella sampling simulations.Elongation factor G bound to the ribosome in an intermediate state of translocation.Crystal Structures of EF-G-Ribosome Complexes Trapped in Intermediate States of Translocation Major centers of motion in the large ribosomal RNAs The role of L1 stalk-tRNA interaction in the ribosome elongation cycle Interrupted catalysis: the EF4 (LepA) effect on back-translocation.Genome engineering using targeted oligonucleotide libraries and functional selection.Probing translation with small-molecule inhibitors Tuberculosis: Drug discovery goes au naturel.Molecular mechanics of 30S subunit head rotation.Correlated conformational events in EF-G and the ribosome regulate translocation.The DNA-Binding Protein from Starved Cells (Dps) Utilizes Dual Functions To Defend Cells against Multiple Stresses.Ribosomal translocation: one step closer to the molecular mechanism.The complex logic of stringent response regulation in Caulobacter crescentus: starvation signalling in an oligotrophic environment.Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA Reconstitution of Protein Translation of Mycobacterium Reveals Functional Conservation and Divergence with the Gram-Negative Bacterium Escherichia coli Time-kill curve analysis and pharmacodynamic modelling for in vitro evaluation of antimicrobials against Neisseria gonorrhoeae Aminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infections Mechanistic insights into antibiotic action on the ribosome through single-molecule fluorescence imaging Contribution of intersubunit bridges to the energy barrier of ribosomal translocation.Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation.Intersubunit Bridges of the Bacterial Ribosome.Mutation in ribosomal protein S5 leads to spectinomycin resistance in Neisseria gonorrhoeae.Elongation factor G initiates translocation through a power stroke Fluorescently labeled ribosomes as a tool for analyzing antibiotic binding.Inhibition of bacterial ribosome assembly: a suitable drug target?Bases in 16S rRNA important for subunit association, tRNA binding, and translocation.Recurring RNA structural motifs underlie the mechanics of L1 stalk movement.Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux Bacterial Protein Synthesis as a Target for Antibiotic Inhibition.The translation elongation cycle-capturing multiple states by cryo-electron microscopy.Structure-Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions.Structure of AadA from Salmonella enterica: a monomeric aminoglycoside (3'')(9) adenyltransferase.

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A Steric Block in Translation Caused by the Antibiotic Spectinomycin

http://www.wikidata.org/entity/Q27647153

description

2007 nî lūn-bûn

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2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի օգոստոսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

A Steric Block in Translation Caused by the Antibiotic Spectinomycin

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A Steric Block in Translation Caused by the Antibiotic Spectinomycin

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A Steric Block in Translation Caused by the Antibiotic Spectinomycin

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A Steric Block in Translation Caused by the Antibiotic Spectinomycin

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A Steric Block in Translation Caused by the Antibiotic Spectinomycin

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A Steric Block in Translation Caused by the Antibiotic Spectinomycin

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A Steric Block in Translation Caused by the Antibiotic Spectinomycin

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A Steric Block in Translation Caused by the Antibiotic Spectinomycin

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A Steric Block in Translation Caused by the Antibiotic Spectinomycin

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ACS Chemical Biology

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A Steric Block in Translation Caused by the Antibiotic Spectinomycin

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James M Holton

http://www.w3.org/2001/XMLSchema#string

Jamie H D Cate

http://www.w3.org/2001/XMLSchema#string

Kurt Fredrick

http://www.w3.org/2001/XMLSchema#string

Maria A Borovinskaya

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Shinichiro Shoji

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P2860

Basis for prokaryotic specificity of action of aminoglycoside antibiotics.

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

Crystal structure of the ribosome at 5.5 A resolution

The path of messenger RNA through the ribosome

Locking and unlocking of ribosomal motions

Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.

Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation.

Structural basis for aminoglycoside inhibition of bacterial ribosome recycling

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545-52

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scholarly article

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3481003

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10.1021/CB700100N

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8

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2

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17696316

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4624401

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