The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation - Wikidata - wikimedia - TriplyDB

The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation

The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation

http://www.wikidata.org/entity/Q24535650

about

Gephyrin, the enigmatic organizer at GABAergic synapses A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domains Disruption of contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndrome Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice.A locus for an auditory processing deficit and language impairment in an extended pedigree maps to 12p13.31-q14.3.The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesis Under lock and key: spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processes Actin-Dependent Alterations of Dendritic Spine Morphology in Shankopathies The inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors Possible functional links among brain- and skull-related genes selected in modern humans Force-control at cellular membranes F-BAR family proteins, emerging regulators for cell membrane dynamic changes-from structure to human diseases.The BAR Domain Superfamily Proteins from Subcellular Structures to Human Diseases SH3 domain-based phototrapping in living cells reveals Rho family GAP signaling complexes The proposed functions of membrane curvatures mediated by the BAR domain superfamily proteins.Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities Cooperative signaling between Slit2 and Ephrin-A1 regulates a balance between angiogenesis and angiostasis.Secretory pathway-dependent localization of the Saccharomyces cerevisiae Rho GTPase-activating protein Rgd1p at growth sites The F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently.A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity, and memory.Morphological and behavioral characterization of adult mice deficient for SrGAP3.Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.Function and regulation of Tumbleweed (RacGAP50C) in neuroblast proliferation and neuronal morphogenesis.Prefrontal-enriched SLIT1 expression in Old World monkey cortex established during the postnatal development.The F-BAR domain of SRGP-1 facilitates cell-cell adhesion during C. elegans morphogenesis Structural plasticity: mechanisms and contribution to developmental psychiatric disorders Characterization of a complex chromosomal rearrangement using chromosome, FISH, and microarray assays in a girl with multiple congenital abnormalities and developmental delay Regulation of the postsynaptic cytoskeleton: roles in development, plasticity, and disorders.Control of synapse development and plasticity by Rho GTPase regulatory proteins.ArhGAP9, a novel MAP kinase docking protein, inhibits Erk and p38 activation through WW domain binding Reciprocal Relationship between Head Size, an Autism Endophenotype, and Gene Dosage at 19p13.12 Points to AKAP8 and AKAP8L BAR proteins in cancer and blood disorders A Novel Microduplication in the Neurodevelopmental Gene SRGAP3 That Segregates with Psychotic Illness in the Family of a COS Proband Actin Out: Regulation of the Synaptic Cytoskeleton.Fasting and Systemic Insulin Signaling Regulate Phosphorylation of Brain Proteins That Modulate Cell Morphology and Link to Neurological Disorders.Rho-linked genes and neurological disorders.WRP/srGAP3 facilitates the initiation of spine development by an inverse F-BAR domain, and its loss impairs long-term memory.Current knowledge of the large RhoGAP family of proteins.A-kinase anchoring proteins: from protein complexes to physiology and disease

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P2860

The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation

http://www.wikidata.org/entity/Q24535650

description

2002 nî lūn-bûn

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2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

The novel Rho-GTPase activatin ...... e in severe mental retardation

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The novel Rho-GTPase activatin ...... e in severe mental retardation

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The novel Rho-GTPase activatin ...... e in severe mental retardation

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The novel Rho-GTPase activatin ...... e in severe mental retardation

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The novel Rho-GTPase activatin ...... e in severe mental retardation

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The novel Rho-GTPase activatin ...... e in severe mental retardation

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The novel Rho-GTPase activatin ...... e in severe mental retardation

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The novel Rho-GTPase activatin ...... e in severe mental retardation

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The novel Rho-GTPase activatin ...... e in severe mental retardation

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Proceedings of the National Academy of Sciences of the United States of America

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The novel Rho-GTPase activatin ...... e in severe mental retardation

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Birgit Wogatzky

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Dieter Karch

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Dusan Bartsch

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Farida Latif

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Gholamali Tariverdian

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Gudrun A Rappold

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Malgorzata Zatyka

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Stefan Kirsch

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Uwe Leimer

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Volker Endris

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P2860

Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance

A missense mutation in RPS6KA3 (RSK2) responsible for non-specific mental retardation

Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation

An X chromosome-linked gene encoding a protein with characteristics of a rhoGAP predominantly expressed in hematopoietic cells

Directional guidance of neuronal migration in the olfactory system by the protein Slit

Detailed mapping of a congenital heart disease gene in chromosome 3p25

Localization of the human caveolin-3 gene to the D3S18/D3S4163/D3S4539 locus (3p25), in close proximity to the human oxytocin receptor gene. Identification of the caveolin-3 gene as a candidate for deletion in 3p-syndrome

Characterization of the human glutamate receptor subunit 3 gene (GRIA3), a candidate for bipolar disorder and nonspecific X-linked mental retardation

CALL gene is haploinsufficient in a 3p- syndrome patient

Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway

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11754-11759

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scholarly article

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3144906

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10.1073/PNAS.162241099

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18

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99

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11193282

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12195014

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129341

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