The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors
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A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbĪ±Mechanisms of synapse and dendrite maintenance and their disruption in psychiatric and neurodegenerative disordersLet's go bananas: revisiting the endocytic BAR codeControl of Dendritic Spine Morphological and Functional Plasticity by Small GTPasesNon-muscle myosin II in disease: mechanisms and therapeutic opportunitiesActin-Dependent Alterations of Dendritic Spine Morphology in ShankopathiesX-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genesReduced gamma oscillations in a mouse model of intellectual disability: a role for impaired repetitive neurotransmission?Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disabilityDIP/WISH deficiency enhances synaptic function and performance in the Barnes maze.RhoGTPase Regulators Orchestrate Distinct Stages of Synaptic Development.Cdk5 is a New Rapid Synaptic Homeostasis Regulator Capable of Initiating the Early Alzheimer-Like Pathology.A novel in-frame deletion affecting the BAR domain of OPHN1 in a family with intellectual disability and hippocampal alterations.Arf6-GEF BRAG1 regulates JNK-mediated synaptic removal of GluA1-containing AMPA receptors: a new mechanism for nonsyndromic X-linked mental disorder.Ras and Rap signaling in synaptic plasticity and mental disorders.AMPA receptor antagonist NBQX attenuates later-life epileptic seizures and autistic-like social deficits following neonatal seizuresReduced Inhibition within Layer IV of Sert Knockout Rat Barrel Cortex is Associated with Faster Sensory Integration.The X-linked mental retardation protein OPHN1 interacts with Homer1b/c to control spine endocytic zone positioning and expression of synaptic potentiation.Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking.The genetic basis of non-syndromic intellectual disability: a reviewIntellectual disability and autism spectrum disorders: causal genes and molecular mechanisms.Clinical Presentation and Microarray Analysis of Peruvian Children with Atypical Development and/or Aberrant BehaviorRegulation of the postsynaptic cytoskeleton: roles in development, plasticity, and disorders.Control of synapse development and plasticity by Rho GTPase regulatory proteins.Oligophrenin-1 (OPHN1), a gene involved in X-linked intellectual disability, undergoes RNA editing and alternative splicing during human brain development.The guanine nucleotide exchange factor (GEF) Asef2 promotes dendritic spine formation via Rac activation and spinophilin-dependent targeting.Rho/RacGAPs: embarras de richesse?Actin Out: Regulation of the Synaptic Cytoskeleton.WRP/srGAP3 facilitates the initiation of spine development by an inverse F-BAR domain, and its loss impairs long-term memory.TRIO loss of function is associated with mild intellectual disability and affects dendritic branching and synapse function.Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.Rho Kinase Inhibition Is Essential During In Vitro Neurogenesis and Promotes Phenotypic Rescue of Human Induced Pluripotent Stem Cell-Derived Neurons With Oligophrenin-1 Loss of FunctionWhole-genome sequencing identifies a novel ABCB7 gene mutation for X-linked congenital cerebellar ataxia in a large family of Mongolian ancestry.Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses.Anesthetic Sevoflurane Causes Rho-Dependent Filopodial Shortening in Mouse NeuronsLack of the presynaptic RhoGAP protein oligophrenin1 leads to cognitive disabilities through dysregulation of the cAMP/PKA signalling pathway.Early and sustained altered expression of aging-related genes in young 3xTg-AD mice.Regulation of spine and synapse formation by activity-dependent intracellular signaling pathways.How important are Rho GTPases in neurosecretion?Barfly: sculpting membranes at the Drosophila neuromuscular junction.
P2860
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P2860
The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors
description
2009 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« Õ
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@hyw
2009 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ°ÕøÖÕ¶Õ«Õ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
artĆculu cientĆficu espublizĆ”u en 2009
@ast
im Juni 2009 verƶffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedeckĆ½ ÄlĆ”nok (publikovanĆ½ 2009/06/01)
@sk
vÄdeckĆ½ ÄlĆ”nek publikovanĆ½ v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/06/01)
@nl
Š½Š°ŃŠŗŠ¾Š²Š° ŃŃŠ°ŃŃŃ, Š¾ŠæŃŠ±Š»ŃŠŗŠ¾Š²Š°Š½Š° Š² ŃŠµŃŠ²Š½Ń 2009
@uk
Ł
ŁŲ§ŁŲ© Ų¹ŁŁ
ŁŲ© (ŁŲ“Ų±ŲŖ ŁŁ ŁŁŁŁŁ 2009)
@ar
name
The Rho-linked mental retardat ...... by stabilizing AMPA receptors
@ast
The Rho-linked mental retardat ...... by stabilizing AMPA receptors
@en
The Rho-linked mental retardat ...... by stabilizing AMPA receptors
@nl
type
label
The Rho-linked mental retardat ...... by stabilizing AMPA receptors
@ast
The Rho-linked mental retardat ...... by stabilizing AMPA receptors
@en
The Rho-linked mental retardat ...... by stabilizing AMPA receptors
@nl
prefLabel
The Rho-linked mental retardat ...... by stabilizing AMPA receptors
@ast
The Rho-linked mental retardat ...... by stabilizing AMPA receptors
@en
The Rho-linked mental retardat ...... by stabilizing AMPA receptors
@nl
P2093
P2860
P3181
P356
P1433
P1476
The Rho-linked mental retardat ...... by stabilizing AMPA receptors
@en
P2093
Akiko Nakano-Kobayashi
Linda Van Aelst
Roberto Malinow
P2860
P304
P3181
P356
10.1101/GAD.1783809
P577
2009-06-01T00:00:00Z