Preferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damage
about
Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage responseA PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombinationCellular functions of human RPA1. Multiple roles of domains in replication, repair, and checkpointsInhibition of topoisomerase I prevents chromosome breakage at common fragile sitesInvolvement of nucleotide excision and mismatch repair mechanisms in double strand break repairManaging Single-Stranded DNA during Replication Stress in Fission YeastWhat goes on must come off: phosphatases gate-crash the DNA damage responseRPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage responseHuman CtIP mediates cell cycle control of DNA end resection and double strand break repairEffect of full flavor and denicotinized cigarettes exposure on the brain microvascular endothelium: a microarray-based gene expression study using a human immortalized BBB endothelial cell lineRFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks.Differential involvement of phosphatidylinositol 3-kinase-related protein kinases in hyperphosphorylation of replication protein A2 in response to replication-mediated DNA double-strand breaks.Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responsesPhosphorylation of nucleotide excision repair factor xeroderma pigmentosum group A by ataxia telangiectasia mutated and Rad3-related-dependent checkpoint pathway promotes cell survival in response to UV irradiation.Regulation of replication protein A functions in DNA mismatch repair by phosphorylation.Herpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection.RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint.Structural characterization of human RPA sequential binding to single-stranded DNA using ssDNA as a molecular ruler.Regulatory functions of the N-terminal domain of the 70-kDa subunit of replication protein A (RPA)Human replication protein A-Rad52-single-stranded DNA complex: stoichiometry and evidence for strand transfer regulation by phosphorylation.Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stressHyperphosphorylation of replication protein A in cisplatin-resistant and -sensitive head and neck squamous cell carcinoma cell linesThe role of RPA2 phosphorylation in homologous recombination in response to replication arrestReplication protein A: directing traffic at the intersection of replication and repair.Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex.RING finger and WD repeat domain 3 (RFWD3) associates with replication protein A (RPA) and facilitates RPA-mediated DNA damage response.Interplay of DNA damage and cell cycle signaling at the level of human replication protein ADNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe.Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery.Replication-mediated disassociation of replication protein A-XPA complex upon DNA damage: implications for RPA handing off.DNA-PK, ATM and ATR collaboratively regulate p53-RPA interaction to facilitate homologous recombination DNA repairDistinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice.Non-canonical β-catenin degradation mediates reactive oxygen species-induced epidermal cell death.Phosphorylation and cellular function of the human Rpa2 N-terminus in the budding yeast Saccharomyces cerevisiae.The DNA damage response and checkpoint adaptation in Saccharomyces cerevisiae: distinct roles for the replication protein A2 (Rfa2) N-terminus.WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes.Cdk5 promotes DNA replication stress checkpoint activation through RPA-32 phosphorylation, and impacts on metastasis free survival in breast cancer patients.Human single-stranded DNA binding proteins: guardians of genome stability.E2F6 inhibits cobalt chloride-mimetic hypoxia-induced apoptosis through E2F1.
P2860
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P2860
Preferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damage
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Preferential localization of h ...... oint complexes upon DNA damage
@ast
Preferential localization of h ...... oint complexes upon DNA damage
@en
Preferential localization of h ...... oint complexes upon DNA damage
@nl
type
label
Preferential localization of h ...... oint complexes upon DNA damage
@ast
Preferential localization of h ...... oint complexes upon DNA damage
@en
Preferential localization of h ...... oint complexes upon DNA damage
@nl
prefLabel
Preferential localization of h ...... oint complexes upon DNA damage
@ast
Preferential localization of h ...... oint complexes upon DNA damage
@en
Preferential localization of h ...... oint complexes upon DNA damage
@nl
P2093
P2860
P356
P1433
P1476
Preferential localization of h ...... oint complexes upon DNA damage
@en
P2093
Xiaoming Wu
Yiyong Liu
Zhengguan Yang
P2860
P304
P356
10.1042/BJ20050379
P407
P577
2005-11-01T00:00:00Z