Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation
about
Crucial structural role for the PH and C1 domains of the Vav1 exchange factorSGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis.Vav family exchange factors: an integrated regulatory and functional viewStructural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1LOVTRAP: an optogenetic system for photoinduced protein dissociationStructural basis for a novel interaction between TXNIP and Vav2Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targetingAn active form of Vav1 induces migration of mammary epithelial cells by stimulating secretion of an epidermal growth factor receptor ligandLigand-independent activation of androgen receptors by Rho GTPase signaling in prostate cancerChlamydial entry involves TARP binding of guanine nucleotide exchange factors.Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes.Molecular basis for failure of "atypical" C1 domain of Vav1 to bind diacylglycerol/phorbol ester.Kalirin/Trio Rho guanine nucleotide exchange factors regulate a novel step in secretory granule maturationRap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factorsPaxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and migrationPLEKHG3 enhances polarized cell migration by activating actin filaments at the cell frontCritical role of the pleckstrin homology and cysteine-rich domains in Vav signaling and transforming activity.Remedial strategies in structural proteomics: expression, purification, and crystallization of the Vav1/Rac1 complex.Critical role of the pleckstrin homology domain in Dbs signaling and growth regulation.Requirement for C-terminal sequences in regulation of Ect2 guanine nucleotide exchange specificity and transformation.High frequency of genetic aberrations in enteropathy-type T-cell lymphoma.
P2860
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P2860
Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation
description
2002 nî lūn-bûn
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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2002 թվականի ապրիլին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
Critical but distinct roles fo ...... 2 signaling and transformation
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Critical but distinct roles fo ...... 2 signaling and transformation
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Critical but distinct roles fo ...... 2 signaling and transformation
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type
label
Critical but distinct roles fo ...... 2 signaling and transformation
@ast
Critical but distinct roles fo ...... 2 signaling and transformation
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Critical but distinct roles fo ...... 2 signaling and transformation
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prefLabel
Critical but distinct roles fo ...... 2 signaling and transformation
@ast
Critical but distinct roles fo ...... 2 signaling and transformation
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Critical but distinct roles fo ...... 2 signaling and transformation
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P2093
P2860
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Critical but distinct roles fo ...... 2 signaling and transformation
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Channing J Der
Michelle A Booden
Sharon L Campbell
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P304
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P356
10.1128/MCB.22.8.2487-2497.2002
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P577
2002-04-01T00:00:00Z