Cartilage oligomeric matrix protein-deficient mice have normal skeletal development.
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Cartilage oligomeric matrix protein is involved in human limb development and in the pathogenesis of osteoarthritisWISP3, the gene responsible for the human skeletal disease progressive pseudorheumatoid dysplasia, is not essential for skeletal function in miceA mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasiaCollagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleatorsDecreased chondrocyte proliferation and dysregulated apoptosis in the cartilage growth plate are key features of a murine model of epiphyseal dysplasia caused by a matn3 mutation.Storage function of cartilage oligomeric matrix protein: the crystal structure of the coiled-coil domain in complex with vitamin D(3).Influences of the N700S Thrombospondin-1 Polymorphism on Protein Structure and StabilitySkeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagenMice with a disruption of the thrombospondin 3 gene differ in geometric and biomechanical properties of bone and have accelerated development of the femoral headDerlin-2-deficient mice reveal an essential role for protein dislocation in chondrocytesPhylogenomic analysis of vertebrate thrombospondins reveals fish-specific paralogues, ancestral gene relationships and a tetrapod innovation.Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis.Age-related changes in the extracellular matrix of nucleus pulposus and anulus fibrosus of human intervertebral disc.Control of organization and function of muscle and tendon by thrombospondin-4.Cartilage oligomeric matrix protein (COMP) in murine brachiocephalic and carotid atherosclerotic lesions.Pseudoachondroplasia/COMP - translating from the bench to the bedside.Elevated Levels of Cartilage Oligomeric Matrix Protein during In Vitro Cartilage Matrix Generation Decrease Collagen Fibril Diameter.The thrombospondins.Unique matrix structure in the rough endoplasmic reticulum cisternae of pseudoachondroplasia chondrocytes.Transcriptomic diversification of developing cumulus and mural granulosa cells in mouse ovarian follicles.Cartilage oligomeric matrix protein enhances matrix assembly during chondrogenesis of human mesenchymal stem cells.A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia.Collagen XII and XIV, new partners of cartilage oligomeric matrix protein in the skin extracellular matrix suprastructure.New therapeutic targets in rare genetic skeletal diseases.Cartilage oligomeric matrix protein specific antibodies are pathogenicComparative proteomic analysis of normal and collagen IX null mouse cartilage reveals altered extracellular matrix composition and novel components of the collagen IX interactome.Microarray analysis identifies COMP as the most differentially regulated transcript throughout in vitro follicle growth.Ribozyme-mediated reduction of wild-type and mutant cartilage oligomeric matrix protein (COMP) mRNA and proteinSkeletal dysplasias associated with mild myopathy-a clinical and molecular review.What we should know before using tissue engineering techniques to repair injured tendons: a developmental biology perspectiveThrombospondin-4, tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14: novel extracellular matrix modulating factors in cardiac remodelling.The role of the non-collagenous matrix in tendon function.Extracellular matrix and developing growth plate.Novel therapeutic interventions for pseudoachondroplasia.Pseudoachondroplasia is caused through both intra- and extracellular pathogenic pathways.Altered integration of matrilin-3 into cartilage extracellular matrix in the absence of collagen IX.Secretion of cartilage oligomeric matrix protein is affected by the signal peptide.Matrilin-3 is dispensable for mouse skeletal growth and development.Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP).Chop (Ddit3) is essential for D469del-COMP retention and cell death in chondrocytes in an inducible transgenic mouse model of pseudoachondroplasia.
P2860
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P2860
Cartilage oligomeric matrix protein-deficient mice have normal skeletal development.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cartilage oligomeric matrix protein-deficient mice have normal skeletal development
@nl
Cartilage oligomeric matrix protein-deficient mice have normal skeletal development.
@ast
Cartilage oligomeric matrix protein-deficient mice have normal skeletal development.
@en
type
label
Cartilage oligomeric matrix protein-deficient mice have normal skeletal development
@nl
Cartilage oligomeric matrix protein-deficient mice have normal skeletal development.
@ast
Cartilage oligomeric matrix protein-deficient mice have normal skeletal development.
@en
prefLabel
Cartilage oligomeric matrix protein-deficient mice have normal skeletal development
@nl
Cartilage oligomeric matrix protein-deficient mice have normal skeletal development.
@ast
Cartilage oligomeric matrix protein-deficient mice have normal skeletal development.
@en
P2093
P2860
P1476
Cartilage oligomeric matrix protein-deficient mice have normal skeletal development.
@en
P2093
Ake Oldberg
Attila Aszódi
Dick Heinegård
Ernst B Hunziker
Finn P Reinholt
Liz Svensson
P2860
P304
P356
10.1128/MCB.22.12.4366-4371.2002
P407
P577
2002-06-01T00:00:00Z