Matrilin-3 is dispensable for mouse skeletal growth and development.
about
WISP3, the gene responsible for the human skeletal disease progressive pseudorheumatoid dysplasia, is not essential for skeletal function in miceDecreased chondrocyte proliferation and dysregulated apoptosis in the cartilage growth plate are key features of a murine model of epiphyseal dysplasia caused by a matn3 mutation.Collagen XXVIII, a novel von Willebrand factor A domain-containing protein with many imperfections in the collagenous domainFunctional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritisDerlin-2-deficient mice reveal an essential role for protein dislocation in chondrocytesHand radiology characteristics of patients carrying the T(303)M mutation in the gene for matrilin-3.Matrilin-3 inhibits chondrocyte hypertrophy as a bone morphogenetic protein-2 antagonist.Unique matrix structure in the rough endoplasmic reticulum cisternae of pseudoachondroplasia chondrocytes.Neutral sphingomyelinase (SMPD3) deficiency causes a novel form of chondrodysplasia and dwarfism that is rescued by Col2A1-driven smpd3 transgene expressionThe matrilins--adaptor proteins in the extracellular matrix.New therapeutic targets in rare genetic skeletal diseases.Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4Extracellular matrix and developing growth plate.Altered integration of matrilin-3 into cartilage extracellular matrix in the absence of collagen IX.Zebrafish (Danio rerio) matrilins: shared and divergent characteristics with their mammalian counterpartsMatrilin-1 is essential for zebrafish development by facilitating collagen II secretion
P2860
Q24558691-530C0B35-D408-4C34-A181-54A7D894AAABQ24653702-37A440E2-1D3B-4C67-A1CA-14097CB9FB47Q28510535-D23CCD0B-B7C3-463A-8439-57C105ABD71EQ28586673-06816629-F2A1-4F96-A92F-E228A31E47BEQ28593497-CC4E42CB-10B0-4BDF-8981-8BFDEC11D33BQ34517993-D16E0506-F767-440D-98C6-67FC301DF1CAQ34683323-47417143-BAED-442E-89E3-D88E6F74F02CQ35570417-D828DA73-3606-4CCC-A9AB-00CF1C0309D9Q35928277-4E1E7944-B2B8-484F-ACFD-2100A7E12242Q36156037-D8071ED5-C655-4ECA-A0B3-60AA6E01C38DQ36275329-17932F02-D91B-48A5-B243-A47FE09B9066Q37272076-09F5F4A5-3670-4D63-94AE-A3610B05ADD7Q38248420-C8BB06F4-51A9-41D6-9D37-B0C0AA3019C0Q39891469-6816E7A5-66DE-4AC8-B79E-284FD49D028BQ40482900-9389C56A-7BE6-4996-9D07-72698C3B0C1CQ41876408-C48505A7-8B35-4864-9B60-49EA2D88AEAD
P2860
Matrilin-3 is dispensable for mouse skeletal growth and development.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Matrilin-3 is dispensable for mouse skeletal growth and development.
@en
type
label
Matrilin-3 is dispensable for mouse skeletal growth and development.
@en
prefLabel
Matrilin-3 is dispensable for mouse skeletal growth and development.
@en
P2093
P2860
P1476
Matrilin-3 is dispensable for mouse skeletal growth and development.
@en
P2093
Attila Aszódi
Birgit Kobbe
Claudia Nicolae
Mats Paulsson
Nicolai Miosge
Raimund Wagener
P2860
P304
P356
10.1128/MCB.24.4.1691-1699.2004
P407
P577
2004-02-01T00:00:00Z