Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia
about
Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytesThe anionic conjugates of bilirubin and bile acids stimulate ATP hydrolysis by S-(dinitrophenyl)glutathione ATPase of human erythrocyteRegulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptorThe MRP2/cMOAT transporter and arsenic-glutathione complex formation are required for biliary excretion of arsenic.Electron-microscopic demonstration of multidrug resistance protein 2 (Mrp2) retrieval from the canalicular membrane in response to hyperosmolarity and lipopolysaccharide.Retrieval of the mrp2 gene encoded conjugate export pump from the canalicular membrane contributes to cholestasis induced by tert-butyl hydroperoxide and chloro-dinitrobenzene.Defective ATP-dependent bile canalicular transport of organic anions in mutant (TR-) rats with conjugated hyperbilirubinemia.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Biliary secretion of S-nitrosoglutathione is involved in the hypercholeresis induced by ursodeoxycholic acid in the normal rat.Hepatic glutathione and glutathione S-conjugate transport mechanismsThe MRP family of drug efflux pumps.ATP-dependent transport of organic anions in secretory vesicles of Saccharomyces cerevisiaeOverexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.Function and regulation of multidrug resistance proteins (MRPs) in the renal elimination of organic anions.Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cellsHepatic basolateral efflux contributes significantly to rosuvastatin disposition II: characterization of hepatic elimination by basolateral, biliary, and metabolic clearance pathways in rat isolated perfused liver.Rat liver canalicular membrane vesicles contain an ATP-dependent bile acid transport system.Cellular localization and biochemical analysis of mammalian CDC50A, a glycosylated β-subunit for P4 ATPases.Glutathione conjugation and conversion to mercapturic acids can occur as an intrahepatic process.Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione.ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids.Bilirubin glucuronidation by intact Gunn rat fibroblasts expressing bilirubin UDP-glucuronosyltransferase.Regulation of organic anion transport in the liver.Glutathione-conjugate transport by human colon adenocarcinoma cells (Caco-2 cells)Organic anions exhibit distinct inhibition patterns on the low-Km and high-Km transport of S-(2,4-dinitrophenyl)glutathione through the human erythrocyte membrane.Dexamethasone- and osmolarity-dependent expression of the multidrug-resistance protein 2 in cultured rat hepatocytes.Modulation of biotransformation systems and ABC transporters by benznidazole in rats.Induction of the multispecific organic anion transporter (cMoat/mrp2) gene and biliary glutathione secretion by the herbicide 2,4,5-trichlorophenoxyacetic acid in the mouse liver.Impaired activity of the bile canalicular organic anion transporter (Mrp2/cmoat) is not the main cause of ethinylestradiol-induced cholestasis in the rat.Inhibition of glutathione-conjugate secretion from isolated hepatocytes by dipolar bile acids and other organic anions.Hepatocanalicular organic-anion transport is regulated by protein kinase C.ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump.Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells.ATP-dependent multispecific organic anion transport system in rat erythrocyte membrane vesicles.ATP-dependent transport of reduced glutathione on YCF1, the yeast orthologue of mammalian multidrug resistance associated proteins.
P2860
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P2860
Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia
description
1989 nî lūn-bûn
@nan
1989 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
name
Hepatobiliary transport of glu ...... hereditary hyperbilirubinemia
@ast
Hepatobiliary transport of glu ...... hereditary hyperbilirubinemia
@en
Hepatobiliary transport of glu ...... hereditary hyperbilirubinemia
@nl
type
label
Hepatobiliary transport of glu ...... hereditary hyperbilirubinemia
@ast
Hepatobiliary transport of glu ...... hereditary hyperbilirubinemia
@en
Hepatobiliary transport of glu ...... hereditary hyperbilirubinemia
@nl
prefLabel
Hepatobiliary transport of glu ...... hereditary hyperbilirubinemia
@ast
Hepatobiliary transport of glu ...... hereditary hyperbilirubinemia
@en
Hepatobiliary transport of glu ...... hereditary hyperbilirubinemia
@nl
P2093
P2860
P356
P1476
Hepatobiliary transport of glu ...... hereditary hyperbilirubinemia
@en
P2093
P L Jansen
R Ottenhoff
R P Elferink
W Liefting
P2860
P304
P356
10.1172/JCI114189
P407
P577
1989-08-01T00:00:00Z