Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.
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Evidence that human class Theta glutathione S-transferase T1-1 can catalyse the activation of dichloromethane, a liver and lung carcinogen in the mouse. Comparison of the tissue distribution of GST T1-1 with that of classes Alpha, Mu and Pi GST in hThe anthracycline resistance-associated (ara) gene, a novel gene associated with multidrug resistance in a human leukaemia cell lineRole of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analoguesTrypanothione overproduction and resistance to antimonials and arsenicals in LeishmaniaGlutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapyMultidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogsMultidrug resistance-associated protein 1 (MRP1) mediated vincristine resistance: effects of N-acetylcysteine and Buthionine sulfoximineATP-binding cassette (ABC) transporters in normal and pathological lungMammalian P4-ATPases and ABC transporters and their role in phospholipid transportLocalization of the C-terminus of rat glutathione S-transferase A1-1: crystal structure of mutants W21F and W21F/F220YYeast gene YRR1, which is required for resistance to 4-nitroquinoline N-oxide, mediates transcriptional activation of the multidrug resistance transporter gene SNQ2.The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1.A novel membrane-bound glutathione S-transferase functions in the stationary phase of the yeast Saccharomyces cerevisiae.Multiple Pdr1p/Pdr3p binding sites are essential for normal expression of the ATP binding cassette transporter protein-encoding gene PDR5.The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotidesThe yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pumpThe Arabidopsis thaliana ABC transporter AtMRP5 controls root development and stomata movementHomologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegansEndogenous antioxidant enzymes and glutathione S-transferase in protection of mesothelioma cells against hydrogen peroxide and epirubicin toxicityTriggering of protection mechanism against Phoneutria nigriventer spider venom in the brainMajor vault protein LRP-related multidrug resistanceIdentification of the membrane-active regions of the severe acute respiratory syndrome coronavirus spike membrane glycoprotein using a 16/18-mer peptide scan: implications for the viral fusion mechanismDifferential expression of sphingolipids in MRP1 overexpressing HT29 cells.Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1.Cloning and functional analysis of the rhesus macaque ABCG2 gene. Forced expression confers an SP phenotype among hematopoietic stem cell progeny in vivo.Modeling the chemoprotective functions of glutathione S-transferases in cultured cell lines by heterologous expression.Molecular aspects of organic compound transport across the plasma membrane of hepatocytes.Mechanisms of drug resistance in chemotherapy for urogenital carcinoma.Glutathione transport is a unique function of the ATP-binding cassette protein ABCG2.Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier.Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated proteinA family of drug transporters: the multidrug resistance-associated proteins.The human multidrug resistance-associated protein (MRP) gene family: from biological function to drug molecular design.Intermediate structural states involved in MRP1-mediated drug transport. Role of glutathione.Multidrug resistance in tumour cells: characterization of the multidrug resistant cell line K562-Lucena 1.The hydroxyl group of S685 in Walker A motif and the carboxyl group of D792 in Walker B motif of NBD1 play a crucial role for multidrug resistance protein folding and function.Glutathione and drug resistance.Nanodiamond-mitoxantrone complexes enhance drug retention in chemoresistant breast cancer cellsStrategies to overcome simultaneous P-glycoprotein mediated efflux and CYP3A4 mediated metabolism of drugs.Hepatic glutathione and glutathione S-conjugate transport mechanisms
P2860
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P2860
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Overexpression of the gene enc ...... athione S-conjugate transport.
@ast
Overexpression of the gene enc ...... athione S-conjugate transport.
@en
type
label
Overexpression of the gene enc ...... athione S-conjugate transport.
@ast
Overexpression of the gene enc ...... athione S-conjugate transport.
@en
prefLabel
Overexpression of the gene enc ...... athione S-conjugate transport.
@ast
Overexpression of the gene enc ...... athione S-conjugate transport.
@en
P2093
P2860
P356
P1476
Overexpression of the gene enc ...... tathione S-conjugate transport
@en
P2093
P2860
P304
13033-13037
P356
10.1073/PNAS.91.26.13033
P407
P577
1994-12-01T00:00:00Z