Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells - Wikidata - wikimedia - TriplyDB

Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells

Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells

http://www.wikidata.org/entity/Q24562089

about

Digitoxin and its analogs as novel cancer therapeutics Reverse phase protein microarrays advance to use in clinical trials Reduced PARP1 as a Serum Biomarker for Graft Rejection in Kidney Transplantation De novo biosynthetic profiling of high abundance proteins in cystic fibrosis lung epithelial cells.CFTR is a negative regulator of NFkappaB mediated innate immune response.Lack of CFTR in skeletal muscle predisposes to muscle wasting and diaphragm muscle pump failure in cystic fibrosis mice Elevated miR-155 promotes inflammation in cystic fibrosis by driving hyperexpression of interleukin-8 Realizing the promise of reverse phase protein arrays for clinical, translational, and basic research: a workshop report: the RPPA (Reverse Phase Protein Array) society.Cardiac glycosides inhibit TNF-alpha/NF-kappaB signaling by blocking recruitment of TNF receptor-associated death domain to the TNF receptor.Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth.Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization Gender dependence for a subset of the low-abundance signaling proteome in human platelets.Activation of 3-phosphoinositide-dependent kinase 1 (PDK1) and serum- and glucocorticoid-induced protein kinase 1 (SGK1) by short-chain sphingolipid C4-ceramide rescues the trafficking defect of ΔF508-cystic fibrosis transmembrane conductance regula Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers.Cellular location and expression of Na+, K+ -ATPase α subunits affect the anti-proliferative activity of oleandrin.Drug-set enrichment analysis: a novel tool to investigate drug mode of action Toward the pharmacogenomics of cystic fibrosis--an update.Elevated expression levels of ANXA11, integrins β3 and α3, and TNF-α contribute to a candidate proteomic signature in urine for kidney allograft rejection.Ouabain Mimics Low Temperature Rescue of F508del-CFTR in Cystic Fibrosis Epithelial Cells.Heart failure drug digitoxin induces calcium uptake into cells by forming transmembrane calcium channels Cystic fibrosis transmembrane conductance regulator controls lung proteasomal degradation and nuclear factor-kappaB activity in conditions of oxidative stress.Digitoxin as an anticancer agent with selectivity for cancer cells: possible mechanisms involved.cAMP-mediated regulation of cholesterol accumulation in cystic fibrosis and Niemann-Pick type C cells Digitoxin induces apoptosis in cancer cells by inhibiting nuclear factor of activated T-cells-driven c-MYC expression.Chemical biology of inflammatory cytokine signaling.Protein biomarkers in cystic fibrosis research: where next?Cardiac glycosides in cancer therapy: from preclinical investigations towards clinical trials.CHOP transcription factor mediates IL-8 signaling in cystic fibrosis bronchial epithelial cells.Digitoxin for Airway Inflammation in Cystic Fibrosis: Preliminary Assessment of Safety, Pharmacokinetics, and Dose Finding.Influence of interleukin-8 (IL-8) and IL-8 receptors on the migration of human keratinocytes, the role of PLC-γ and potential clinical implications.Validation of Biomarker Proteins Using Reverse Capture Protein Microarrays.Cyclin E and FGF8 are downstream cell growth regulators in distinct tumor suppressor effects of ANXA7 in hormone-resistant cancer cells of breast versus prostate origin

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P2860

Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells

http://www.wikidata.org/entity/Q24562089

description

2004 nî lūn-bûn

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2004 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2004 թվականի մայիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Digitoxin mimics gene therapy ...... fibrosis lung epithelial cells

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Digitoxin mimics gene therapy ...... fibrosis lung epithelial cells

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Digitoxin mimics gene therapy ...... fibrosis lung epithelial cells

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type

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Digitoxin mimics gene therapy ...... fibrosis lung epithelial cells

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Digitoxin mimics gene therapy ...... fibrosis lung epithelial cells

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Digitoxin mimics gene therapy ...... fibrosis lung epithelial cells

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Digitoxin mimics gene therapy ...... fibrosis lung epithelial cells

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Digitoxin mimics gene therapy ...... fibrosis lung epithelial cells

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Digitoxin mimics gene therapy ...... fibrosis lung epithelial cells

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Proceedings of the National Academy of Sciences of the United States of America

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Digitoxin mimics gene therapy ...... fibrosis lung epithelial cells

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P2093

Bette S Pollard

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Catherine Jozwik

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Cloud Paweletz

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Eliahu Heldman

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Harvey B Pollard

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Hung Caohuy

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Jian Zhang

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Meera Srivastava

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Ofer Eidelman

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QingFeng Yang

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P2860

Identification of the cystic fibrosis gene: chromosome walking and jumping

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

Control of the proinflammatory state in cystic fibrosis lung epithelial cells by genes from the TNF-alphaR/NFkappaB pathway

Identification of the cystic fibrosis gene: genetic analysis

Degradation of CFTR by the ubiquitin-proteasome pathway

Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays.

Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front.

Multiple control of interleukin-8 gene expression.

Pharmacokinetics and bioavailability of aerosolized tobramycin in cystic fibrosis.

Barriers to and new approaches for gene therapy and gene delivery in cystic fibrosis.

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scholarly article

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10.1073/PNAS.0402030101

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20

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101

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Kenneth A. Jacobson

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2004-05-10T00:00:00Z

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8568681

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15136726

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cystic fibrosis

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419668

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