Activation of 3-phosphoinositide-dependent kinase 1 (PDK1) and serum- and glucocorticoid-induced protein kinase 1 (SGK1) by short-chain sphingolipid C4-ceramide rescues the trafficking defect of ΔF508-cystic fibrosis transmembrane conductance regula
about
SGK1: The Dark Side of PI3K Signaling.Bacterial Sphingomyelinase is a State-Dependent Inhibitor of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR)Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration.Hallmarks of therapeutic management of the cystic fibrosis functional landscape.Repairing the basic defect in cystic fibrosis - one approach is not enough.MicroRNA profiling identifies miR-129-5p as a regulator of EMT in tubular epithelial cells.miR-16 rescues F508del-CFTR function in native cystic fibrosis epithelial cells.Ubiquitination and the Regulation of Membrane Proteins.Inhibition of mTORC2 component RICTOR impairs tumor growth in pancreatic cancer models.
P2860
Q30399129-D97389C2-A4B9-4E78-B26C-8D008B2D789DQ33774155-F9C29D75-AE64-4152-BE5A-CC6E38E713E9Q34531992-0FD61776-52B6-4140-946C-2106F09DD57CQ36279553-520D2A93-5E47-4B48-B39E-75D7A066EF5AQ38594795-D2CDD6D4-C2FF-4047-A52D-295C7A46131CQ38793540-DE2E7D43-9343-4399-A69C-B4A99BC4B37AQ38857990-0F28A9AA-811A-4D2E-ACA8-6C25327EAC24Q39033646-90674482-D2BF-46F5-82F5-49DB903BEB72Q41781449-4771FBAE-CD4C-4CA0-B7B8-D2921DA97E28
P2860
Activation of 3-phosphoinositide-dependent kinase 1 (PDK1) and serum- and glucocorticoid-induced protein kinase 1 (SGK1) by short-chain sphingolipid C4-ceramide rescues the trafficking defect of ΔF508-cystic fibrosis transmembrane conductance regula
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Activation of 3-phosphoinositi ...... ansmembrane conductance regula
@ast
Activation of 3-phosphoinositi ...... ansmembrane conductance regula
@en
Activation of 3-phosphoinositide-dependent kinase 1
@nl
type
label
Activation of 3-phosphoinositi ...... ansmembrane conductance regula
@ast
Activation of 3-phosphoinositi ...... ansmembrane conductance regula
@en
Activation of 3-phosphoinositide-dependent kinase 1
@nl
prefLabel
Activation of 3-phosphoinositi ...... ansmembrane conductance regula
@ast
Activation of 3-phosphoinositi ...... ansmembrane conductance regula
@en
Activation of 3-phosphoinositide-dependent kinase 1
@nl
P2093
P2860
P356
P1476
Activation of 3-phosphoinositi ...... ansmembrane conductance regula
@en
P2093
Andrew E Xu
Catherine Jozwik
Harvey B Pollard
Hung Caohuy
Matthew Glover
Qingfeng Yang
Raymond A Frizzell
Thien-An Ha
Yvonne Eudy
P2860
P304
35953-35968
P356
10.1074/JBC.M114.598649
P407
P577
2014-11-10T00:00:00Z