Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin - Wikidata - wikimedia - TriplyDB

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

http://www.wikidata.org/entity/Q24563629

about

FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3 FANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCL Molecular pathogenesis and clinical management of Fanconi anemia How the fanconi anemia pathway guards the genome Impaired nucleotide excision repair upon macrophage differentiation is corrected by E1 ubiquitin-activating enzyme Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway Interplay between Fanconi anemia and homologous recombination pathways in genome integrity The Fanconi anemia pathway and DNA interstrand cross-link repair Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2 Insights into Fanconi Anaemia from the structure of human FANCE The structure of the catalytic subunit FANCL of the Fanconi anemia core complex Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair Use of poly ADP-ribose polymerase [PARP] inhibitors in cancer cells bearing DDR defects: the rationale for their inclusion in the clinic Predictors and Modulators of Synthetic Lethality: An Update on PARP Inhibitors and Personalized Medicine Mouse models of Fanconi anemia FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights Overexpression of Rad51C splice variants in colorectal tumors FANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathway Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway Expanded roles of the Fanconi anemia pathway in preserving genomic stability The Fanconi anemia pathway and ubiquitin FANCD2 monoubiquitination and activation by hexavalent chromium [Cr(VI)] exposure: activation is not required for repair of Cr(VI)-induced DSBs An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication.Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction.The role of the Fanconi anemia network in the response to DNA replication stress.Fanconi anemia proteins stabilize replication forks.The ubiquitin system, disease, and drug discovery.Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination.A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage.Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage.Hypersensitivity of primordial germ cells to compromised replication-associated DNA repair involves ATM-p53-p21 signaling Significance of the Fanconi anemia FANCD2 protein in sporadic and metastatic human breast cancer Cul4A is essential for spermatogenesis and male fertility.Human HEL308 localizes to damaged replication forks and unwinds lagging strand structures The Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization.RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network.Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.

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P2860

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

http://www.wikidata.org/entity/Q24563629

description

2004 nî lūn-bûn

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2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2004 թվականի հուլիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

@ast

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

@en

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

@nl

type

label

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

@ast

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

@en

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

@nl

prefLabel

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

@ast

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

@en

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

@nl

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MCB.24.13.5850-5862.2004

P1433

Molecular and Cellular Biology

P1476

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

@en

P2093

Alan D D'Andrea

http://www.w3.org/2001/XMLSchema#string

Paul R Andreassen

http://www.w3.org/2001/XMLSchema#string

XiaoZhe Wang

http://www.w3.org/2001/XMLSchema#string

P2860

ATM-dependent phosphorylation of nibrin in response to radiation exposure

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

FANCE: the link between Fanconi anaemia complex assembly and activity

Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex

Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein

The BRCA2 gene product functionally interacts with p53 and RAD51

A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway

BRCA1-independent ubiquitination of FANCD2

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5850-62

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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2659800

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10.1128/MCB.24.13.5850-5862.2004

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13

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24

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2004-07-01T00:00:00Z

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15199141

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480901

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